Biosynthesized Vitis vinifera seed gold nanoparticles induce apoptotic cell death in A431 skin cancer cells

• Published in: RSC advances Vol. 6; no. 85; pp. 82205 - 82218
• Main Authors: Nirmala, J. Grace, Akila, S., Nadar, M. S. A. Muthukumar, Narendhirakannan, R. T., Chatterjee, Suvro
• Format: Journal Article
• Language: English
• Published: 01.01.2016
• Subjects: ambient temperature; antineoplastic agents; Apoptosis; Cancer; chemical constituents of plants; cytotoxicity; Fourier transform infrared spectroscopy; Gold; human cell lines; inhibitory concentration 50; Killing; light scattering; membrane potential; Membranes; mitochondrial membrane; nanogold; Nanoparticles; neoplasm cells; particle size; reducing agents; Seeds; skin neoplasms; Transmission electron microscopy; Vitis vinifera; X-ray diffraction; zeta potential

Biologically synthesized gold nanoparticles provide many useful characteristics and can be used as carriers to deliver drugs because they are non-toxic and inert. In the present study, phytochemicals present in Vitis vinifera seeds were utilized as reducing agents for the synthesis of gold nanoparti...