Identification of human immunodeficiency virus type-1 subtypes by heteroduplex mobility assay

• Published in: Medical journal. Armed Forces India Vol. 63; no. 3; pp. 249 - 252
• Main Authors: Sahni, AK, Gupta, RM, Nagendra, A, Nema, SK, Rai, R, Bhardwaj, JR
• Format: Journal Article
• Language: English
• Published: India Elsevier B.V 01.07.2007; Elsevier
• Subjects: Heteroduplex mobility assay; HIV-1; India; Original; Subtypes; HIV-1; Heteroduplex mobility assay; Subtypes; India

Background: Human immunodeficiency virus type-1 (HIV-1) has developed marked genomic sequence differences over the course of an epidemic because of an error prone reverse transcriptase (RT), which rapidly incorporates mutations resulting in genomic diversity, altered cell tropism, immune escape and...