Antinuclear antibody (ANA) positivity pattern by line immunoassay in a hospital from eastern India: Update from a laboratory perspective

• Published in: Journal of family medicine and primary care Vol. 13; no. 4; pp. 1254 - 1261
• Main Authors: Banerjee, Ayan, Ranjan, Alok, Kumar, Mukunda, Kumar, Sushil, Bansal, Akash, Mahto, Mala
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer Medknow Publications 01.04.2024
• Subjects: ana profile; autoimmune diseases (ads); line immunoassay (lia); mctd; overlap syndromes; autoimmune diseases (ADs); line immunoassay (LIA); MCTD; overlap syndromes; ANA profile

The existence of more than one antibody in systemic autoimmune rheumatic diseases (SARDs) or connective tissue disease (CTD) along with features of more than one autoimmune disease (AD) in an individual is suggestive of overlap syndrome (OS). Line immunoassay (LIA) can target many autoantibodies in...