Toward robust quantification of dopamine and serotonin in mixtures using nano-graphitic carbon sensors

• Published in: Analyst (London) Vol. 149; no. 8; pp. 2351 - 2362
• Main Authors: Jamalzadeh, Moeid, Cuniberto, Edoardo, Huang, Zhujun, Feeley, Ryan M, Patel, Jyoti C, Rice, Margaret E, Uichanco, Joline, Shahrjerdi, Davood
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 15.04.2024
• Subjects: Analytical chemistry; Brain; Carbon; Carbon Fiber; Carbon fibers; Chemical sensors; Dopamine; Electrochemical analysis; Electrochemical Techniques - methods; Error analysis; Graphite; Low concentrations; Microelectrodes; Mixtures; Prediction models; Robustness; Sensors; Serotonin; Signal monitoring; Voltammetry; Waveforms

Monitoring the coordinated signaling of dopamine (DA) and serotonin (5-HT) is important for advancing our understanding of the brain. However, the co-detection and robust quantification of these signals at low concentrations is yet to be demonstrated. Here, we present the quantification of DA and 5-...