Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein

• Published in: Journal of investigative dermatology Vol. 143; no. 12; pp. 2346 - 2355.e10
• Main Authors: Tahara, Umi, Matsui, Takeshi, Atsugi, Toru, Fukuda, Keitaro, Terooatea, Tommy W, Minoda, Aki, Kubo, Akiharu, Amagai, Masayuki
• Format: Journal Article
• Language: English
• Published: United States 01.12.2023
• Subjects: Animals; Carcinoma, Squamous Cell; Epidermis; Female; Hair Follicle; Hemoglobins; Humans; Keratinocytes; Mice; RNA, Messenger - genetics

The epidermis, the keratinized stratified squamous epithelium surrounding the body surface, offers a valuable framework to investigate how terrestrial animals overcome environmental stresses. However, the mechanisms underlying epidermal barrier function remain nebulous. In this study, we examined ge...