Fatty acid epoxidation by Collariella virescens peroxygenase and heme-channel variants

• Published in: Catalysis science & technology Vol. 10; no. 3; pp. 717 - 725
• Main Authors: González-Benjumea, Alejandro, Carro, Juan, Renau-Mínguez, Chantal, Linde, Dolores, Fernández-Fueyo, Elena, Gutiérrez, Ana, Martínez, Angel T.
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 07.02.2020
• Subjects: Derivatives; E coli; Enzymes; Epoxidation; Fatty acids; Gene expression; Hydroxylation; Occlusion; Oleic acid; Oxygenation; Phenylalanine

Enzyme-driven oxygenation reactions are in the spotlight for organic synthesis. In this regard, a heme-thiolate unspecific peroxygenase (UPO) from the fungus Chaetomium globosum has recently proven to be a suitable catalyst for selective epoxidation of unsaturated fatty acids in the context of the b...