1H NMR-based metabolomics approach to evaluate the effect of Xue-Fu-Zhu-Yu decoction on hyperlipidemia rats induced by high-fat diet

• Published in: Journal of pharmaceutical and biomedical analysis Vol. 78-79; pp. 202 - 210
• Main Authors: Song, Xingfang, Wang, Junsong, Wang, Pengran, Tian, Na, Yang, Minghua, Kong, Lingyi
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 05.05.2013
• Subjects: 1H NMR spectroscopy; Hyperlipidemia; Metabolomics; OPLS-DA; Traditional Chinese medicines; Xue-Fu-Zhu-Yu decoction; Traditional Chinese medicines; Metabolomics; 1H NMR spectroscopy; Hyperlipidemia; OPLS-DA; Xue-Fu-Zhu-Yu decoction

[Display omitted] ► Effect of XFZYD on hyperlipidemia rats were investigated by NMR-based metabolomics. ► Seventeen marker metabolites were indentified to be hyperlipidemia concerned. ► Six isolated pathways were identified to be implicated in hyperlipidemia. ► The anti-hyperlipidemia efficacy of XF...