Episodic memory loss is related to hippocampal-mediated  -amyloid deposition in elderly subjects

• Published in: Brain (London, England : 1878) Vol. 132; no. 5; pp. 1310 - 1323
• Main Authors: Mormino, E. C., Kluth, J. T., Madison, C. M., Rabinovici, G. D., Baker, S. L., Miller, B. L., Koeppe, R. A., Mathis, C. A., Weiner, M. W., Jagust, W. J.
• Format: Journal Article
• Language: English
• Published: Oxford Oxford Publishing Limited (England) 01.05.2009
• ISSN: 0006-8950; 1460-2156
• DOI: 10.1093/brain/awn320

Although β-amyloid (Aβ) plaques are a primary diagnostic criterion for Alzheimer's disease, this pathology is commonly observed in the brains of non-demented older individuals. To explore the importance of this pathology in the absence of dementia, we compared levels of amyloid deposition (via...