Bilateral Occlusive Vasculitis Associated with Retinitis Pigmentosa - A Case Report

• Published in: Ocular immunology and inflammation Vol. 31; no. 1; pp. 215 - 219
• Main Authors: Anthony, Eliza, Baskaran, Prabu, Rajamani, Archana, Rajendran, Anand
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 01.01.2023
• Subjects: Angiogenesis Inhibitors - therapeutic use; CME; Humans; Intravitreal Injections; IOTB; Macular Edema - diagnosis; Macular Edema - drug therapy; Macular Edema - etiology; Male; ranibizumab; Ranibizumab - therapeutic use; Retinal Vein Occlusion - drug therapy; Retinitis pigmentosa; Retinitis Pigmentosa - complications; Retinitis Pigmentosa - diagnosis; Retinitis Pigmentosa - drug therapy; Tomography, Optical Coherence - methods; Treatment Outcome; tuberculous vasculitis; CME; tuberculous vasculitis; Retinitis pigmentosa; IOTB; ranibizumab
• DOI: 10.1080/09273948.2021.1988988
• ISSN: 0927-3948

To report a case of bilateral occlusive vasculitis associated with retinitis pigmentosa (RP). Case report. A 34-year male presented with blurred vision in left eye (OS) for two weeks and right eye (OD) for one day. He had night blindness for five years. His best corrected visual acuity (BCVA) was OD 20/63 and OS 20/200. Ophthalmoscopy revealed bilateral RP with OD inflammatory central retinal vein occlusion (CRVO) and OS occlusive vasculitis with bilateral macular edema. Presumed intraocular tuberculosis (IOTB) was suspected based on clinical features, positive Mantoux and high-resolution computed tomography chest findings. Oral steroids and antitubercular therapy (ATT) were started. OD received six intravitreal ranibizumab injections. At his 7-month follow-up, BCVA improved, OD 20/40 and OS 20/80. RP rarely can be associated with presumed IOTB. Oral steroids with ATT are helpful; however, in inflammatory CRVO, intravitreal ranibizumab can give good results.