Nimbolide Induces Cell Apoptosis via Mediating ER Stress‐Regulated Apoptotic Signaling in Human Oral Squamous Cell Carcinoma - Peng, Bou‐Yue; Wu, Chia‐Yu; Lee, Chia‐Jung; Chang, Tsung‐Ming; Tsao, Ya‐Ting; Liu, Ju‐Fang (Environmental toxicology, 2025)
Keywords: Annexin V; Antineoplastic Agents - pharmacology; antitumor agent; Apoptosis; Apoptosis - drug effects; Asia; Calcium; Calcium (intracellular); Calcium (mitochondrial); Calcium (reticular); Calcium compounds; Cancer; Carcinoma, Squamous Cell - drug therapy; Carcinoma, Squamous Cell - metabolism; Caspase; caspases; Cell cycle; Cell growth; Cell Line, Tumor; Cell proliferation; Cell Proliferation - drug effects; Cell survival; ecotoxicology; Endoplasmic reticulum; endoplasmic reticulum stress; Endoplasmic Reticulum Stress - drug effects; ER stress; Flow cytometry; human oral squamous cell carcinoma; Humans; Limonins - pharmacology; Membrane potential; Membrane Potential, Mitochondrial - drug effects; Mitochondria; mitochondrial membrane; Mouth Neoplasms - drug therapy; Mouth Neoplasms - metabolism; neoplasm cells; Neoplasms; nimbolide; Oral cancer; Oral carcinoma; Oral squamous cell carcinoma; Protein expression; protein synthesis; Proteins; Reactive oxygen species; Reactive Oxygen Species - metabolism; ROS; Signal Transduction - drug effects; Squamous cell carcinoma; therapeutics; Tumor cells; Tumors; viability; Western blotting; Asia; ER stress; antitumor agent; apoptosis; nimbolide; human oral squamous cell carcinoma; ROS