Evaluation of Soluble Tumor Necrosis Factor-Like Weak Inducer of Apoptosis, Omentin, and Tumor Necrosis Factor-α in Subjects with Periodontitis and Type 2 Diabetes Mellitus

• Published in: Genetic testing and molecular biomarkers Vol. 29; no. 1; p. 1
• Main Authors: Ramasundaram, Vinu, Ponnaiyan, Deepa, Anitha, C M, Prakash, P S G, Victor, D J, Singh, Akanksha
• Format: Journal Article
• Language: English
• Published: United States 01.01.2025
• Subjects: Adult; Biomarkers - blood; Cytokine TWEAK - blood; Cytokines - blood; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - genetics; Female; Glycated Hemoglobin - analysis; Glycated Hemoglobin - metabolism; GPI-Linked Proteins - blood; Humans; Lectins - blood; Male; Middle Aged; Periodontitis - blood; Periodontitis - complications; Periodontitis - genetics; Tumor Necrosis Factor-alpha - blood; type 2 diabetes mellitus; TNF-α; omentin-1; sTWEAK; HbA1c; periodontitis

Periodontal disease worsens glycemic control due to the bidirectional link between periodontitis and type 2 diabetes mellitus (T2DM), involving inflammatory markers such as soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK), tumor necrosis factor-α (TNF-α), and omentin-1. However,...