Neural mechanisms of childhood-onset bipolar illness

• Published in: Acta neuropsychiatrica Vol. 12; no. 3; p. 139
• Main Authors: Post, R M, Leverich, G S, Speer, A M, Xing, G, Weiss, S R
• Format: Journal Article
• Language: English
• Published: England 01.09.2000

Substantial evidence exists for a cohort effect (earlier onset and increased prevalence) for both unipolar and bipolar affective disorder in every generation born since World War II. This effect could be related to inherited mechanisms (e.g., bi-Hneal pedigrees or genetic anticipation) or to environ...