The Significance of Serum IgG4/IgG and IgG4/IgG1 Ratio in the Diagnosis Value of IgG4-Related Diseases

• Published in: Discovery medicine Vol. 35; no. 177; p. 476
• Main Authors: Wang, Wei, Li, Yuanyuan, Feng, He
• Format: Journal Article
• Language: English
• Published: United States 01.08.2023
• Subjects: Autoimmune Diseases; Humans; Immunoglobulin G; Immunoglobulin G4-Related Disease - diagnosis; ROC Curve; autoimmune diseases; IgG4/IgG ratio; IgG4-related diseases; IgG4/IgG1 ratio

Elevated serum immunoglobulin G4 (IgG4) is one of the important features of patients with IgG4-related diseases (IgG4-RD). But diagnosing these diseases using IgG4 alone is tricky because the tests can sometimes give inaccurate results. Our research is focused on studying the ratio of IgG4 to two ot...