Immune Checkpoint Inhibitor-Associated Nephrotoxicity

• Published in: Nephron (2015) Vol. 148; no. 1; p. 11
• Main Authors: Mamlouk, Omar, Danesh, Farhad R
• Format: Journal Article
• Language: English
• Published: Switzerland 01.01.2024
• Subjects: Acute Kidney Injury - chemically induced; Acute Kidney Injury - diagnosis; Acute Kidney Injury - therapy; Humans; Immune Checkpoint Inhibitors - adverse effects; Immunosuppressive Agents; Kidney; Retrospective Studies; Nephritis; Onco-nephrology; Immune-related adverse events

The clinical indications for immune checkpoint inhibitors (ICIs) are rapidly expanding. However, adverse events affecting multiple organs, including kidneys leading to ICI-associated acute kidney injury (AKI), remain a significant challenge with ICI therapy. Although AKI is considered a rare complic...