Serum and Tissue Periostin Expression in Rhinosinusitis With Nasal Polyps

• Published in: American journal of rhinology & allergy Vol. 39; no. 4; p. 259
• Main Authors: Danielides, Gerasimos, Lygeros, Spyridon, Kyriakopoulos, Georgios, Tsapardoni, Foteini, Grafanaki, Katerina, Stathopoulos, Constantinos, Naxakis, Stephanos, Danielides, Vassileios
• Format: Journal Article
• Language: English
• Published: United States 01.07.2025
• Subjects: Adult; Aged; Biomarkers - metabolism; Cell Adhesion Molecules - blood; Cell Adhesion Molecules - genetics; Cell Adhesion Molecules - metabolism; Chronic Disease; Female; Humans; Male; Middle Aged; Nasal Mucosa - metabolism; Nasal Mucosa - pathology; Nasal Polyps - blood; Nasal Polyps - genetics; Periostin; Rhinitis - blood; Rhinitis - genetics; Rhinosinusitis; Sinusitis - blood; Sinusitis - genetics; periostin; nasal polyps; nasal mucosa; asthma; allergic rhinitis; Th2 immune response; biomarker; eosinophilic inflammation; rhinosinusitis; rhinology

BackgroundThere is increasing evidence of the contribution of periostin in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP).ObjectiveThis study aims to investigate the expression of periostin in nasal polyp tissue along with serum periostin and its potential function as a biomar...