Clinical Pharmacology of Cyclooxygenase Inhibition and Pharmacodynamic Interaction with Aspirin by Floctafenine in Thai Healthy Subjects - Maenthaisong, R.; Tacconelli, S.; Sritara, P.; Del Boccio, P.; Di Francesco, L.; Sacchetta, P.; Archararit, N.; Aryurachai, K.; Patrignani, P.; Suthisisang, C. (International journal of immunopathology and pharmacology, 2013)
Keywords: Adult; Aspirin - administration & dosage; Aspirin - pharmacology; Blood Platelets - drug effects; Blood Platelets - metabolism; Cross-Over Studies; Cyclooxygenase 1 - blood; Cyclooxygenase 2 - blood; Cyclooxygenase 2 Inhibitors - administration & dosage; Cyclooxygenase 2 Inhibitors - pharmacology; Cyclooxygenase Inhibitors - administration & dosage; Cyclooxygenase Inhibitors - pharmacology; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Healthy Volunteers; Humans; Male; ortho-Aminobenzoates - administration & dosage; ortho-Aminobenzoates - pharmacology; Platelet Aggregation - drug effects; Platelet Aggregation Inhibitors - administration & dosage; Platelet Aggregation Inhibitors - pharmacology; Risk Assessment; Thailand; Thromboxane B2 - blood; Time Factors; Young Adult; nonsteroidal anti-inflammatory drugs; floctafenine; pharmacodynamic interaction; aspirin; COX-2; COX-1