Hypomethylation at PANDAR promoter progressively induces senescence in adipocyte precursor cells in subjects with obesity and type 2 diabetes - Desiderio, Antonella; Pastorino, Monica; Campitelli, Michele; Prevenzano, Immacolata; De Palma, Fatima Domenica Elisa; Spinelli, Rosa; Parrillo, Luca; Longo, Michele; Milone, Marco; Miele, Claudia; Raciti, Gregory Alexander; Beguinot, Francesco (The FASEB journal, 2024)
Keywords: Adipocytes - metabolism; adipose precursor cells; Adult; cellular senescence; Cellular Senescence - genetics; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; DNA Methylation; Female; Humans; lncRNA; Male; Middle Aged; obesity; Obesity - genetics; Obesity - metabolism; PANDAR; Promoter Regions, Genetic; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; type 2 diabetes; adipose precursor cells; cellular senescence; lncRNA; type 2 diabetes; PANDAR; DNA methylation; obesity