Insulin resistance in a large cohort of women with polycystic ovary syndrome: a comparison between euglycaemic-hyperinsulinaemic clamp and surrogate indexes

• Published in: Human reproduction (Oxford) Vol. 32; no. 12; pp. 2515 - 2521
• Main Authors: Tosi, Flavia, Bonora, Enzo, Moghetti, Paolo
• Format: Journal Article
• Language: English
• Published: England 01.12.2017
• Subjects: Adult; Biomarkers - blood; Body Weight; Cohort Studies; Female; Glucose Clamp Technique; Glucose Tolerance Test; Homeostasis; Humans; Hyperandrogenism - therapy; Hyperinsulinism; Insulin Resistance; Obesity - complications; Overweight - complications; Phenotype; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - physiopathology; Polycystic Ovary Syndrome - therapy; Retrospective Studies; ROC Curve; Young Adult; HOMA-IR; PCOS; euglycaemic-hyperinsulinaemic clamp; insulin resistance; PCOS phenotypes

Could surrogate indexes identify insulin resistant individuals among women with polycystic ovary syndrome (PCOS)? Surrogate indexes may be able to rule in, but not rule out, insulin resistance in women with PCOS. Insulin resistance is a typical finding of women with PCOS and most clinical informatio...