Optimal follicle size for human chorionic gonadotropin trigger in mono-follicular growth during letrozole-induced intrauterine insemination cycles: findings from a large retrospective study

• Published in: Fertility and sterility Vol. 124; no. 2; pp. 327 - 333
• Main Authors: Cameron, Krista, Abu-Rafea, Basim, Vilos, Angelos, Hollett-Caines, Jackie, Rebel, Maggie, Van Oirschot, Matthew, Mourad, Ali
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2025
• Subjects: Adult; Chorionic Gonadotropin - administration & dosage; clinical pregnancy rate; Female; Fertility Agents, Female - administration & dosage; follicle size; hCG trigger; Humans; Insemination, Artificial - methods; intrauterine insemination; Letrozole; Letrozole - administration & dosage; Ovarian Follicle - diagnostic imaging; Ovarian Follicle - drug effects; Ovulation Induction - methods; Pregnancy; Pregnancy Rate; Retrospective Studies; hCG trigger; intrauterine insemination; clinical pregnancy rate; Letrozole; follicle size

To determine the optimal lead follicle size for human chorionic gonadotropin trigger in letrozole intrauterine insemination (IUI) cycles, focusing on pregnancy outcomes. Retrospective cohort study. 724 letrozole-IUI cycles conducted at Omega Fertility Clinic between January 1, 2018, and September 30...