In-vitro differentiation of early pig spermatogenic cells to haploid germ cells

• Published in: Molecular human reproduction Vol. 25; no. 9; pp. 507 - 518
• Main Authors: Yu, Kun, Zhang, Yi, Zhang, Bao-Lu, Wu, Han-Yu, Jiang, Wu-Qi, Wang, Su-Tian, Han, De-Ping, Liu, Yi-Xun, Lian, Zheng-Xing, Deng, Shou-Long
• Format: Journal Article
• Language: English
• Published: England 01.09.2019
• Subjects: post-meiotic; in-vitro spermatogenesis; retinoic acid; CREB; piglet; spermatid

Spermatogonial stem cells (SSCs) self-renew and contribute genetic information to the next generation. Pig is wildly used as a model animal for understanding reproduction mechanisms of human being. Inducing directional differentiation of porcine SSCs may be an important strategy in exploring the mec...