Impact of Matrix Metalloproteinases 2 and 9 and Tissue Inhibitor of Metalloproteinase 2 Gene Polymorphisms on Allograft Rejection in Pediatric Renal Transplant Recipients

• Published in: Experimental and clinical transplantation Vol. 21; no. 4; pp. 333 - 337
• Main Authors: Akad Dincer, Selin, Sahin, Feride Iffet, Terzi, Yunus Kasim, Gulleroglu, Kaan, Baskin, Esra, Haberal, Mehmet
• Format: Journal Article
• Language: English
• Published: Turkey 01.04.2023
• Subjects: Adolescent; Adult; Allografts; Child; Genotype; Humans; Kidney Transplantation - adverse effects; Matrix Metalloproteinase 2 - genetics; Matrix Metalloproteinase 2 - metabolism; Matrix Metalloproteinase 9 - genetics; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Tissue Inhibitor of Metalloproteinase-2 - genetics; Tissue Inhibitor of Metalloproteinase-2 - metabolism; Transplant Recipients; Young Adult
• ISSN: 1304-0855; 2146-8427; 2146-8427
• DOI: 10.6002/ect.2020.0036

Acute and chronic allograft rejection have been continuously an important obstacle in the follow-up of renal transplant recipients. During clinical management, several factors acting simultaneously result in acute rejection and chronic allograft nephropathy. Matrix metalloproteinases and tissue inhi...