First-in-human Evaluation of Safety and Dosimetry of [64Cu]FBP8: A fibrin-binding PET Probe - Izquierdo-Garcia, David; Désogère, Pauline; Philip, Anne L.; Sosnovik, David E.; Catana, Ciprian; Caravan, Peter (Molecular imaging and biology, 2025)
Keywords: Adult; Binding; Biodistribution; Blood; Copper Radioisotopes - chemistry; Copper Radioisotopes - pharmacokinetics; Dosimeters; Dosimetry; Estimates; Excretion; Female; Females; Fibrin; Fibrin - metabolism; Fibrosis; Fluorine isotopes; Humans; Imaging; Injection; Lung diseases; Magnetic Resonance Imaging; Male; Males; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Positron emission; Positron emission tomography; Positron-Emission Tomography - methods; Prospective Studies; Radiology; Radiometry; Renal function; Research Article; Thrombosis; Tissue Distribution; Urinary bladder; Young Adult; Fibrin; Positron emission tomography (PET); PET/MRI; Magnetic resonance imaging (MRI); Dosimetry; Effective dose; Probe; Biodistribution; Blood clots