Chromatin retained MUSHER lncRNA integrates ABA and DOG1 signalling pathways to enhance Arabidopsis seeds dormancy

• Published in: Nature communications Vol. 16; no. 1; pp. 7545 - 18
• Main Authors: Sacharowski, Sebastian Przemyslaw, Krzyszton, Michal, Brzezniak, Lien, Rogowski, Karol Jerzy, Montez, Miguel, Rosol, Katarzyna, Wrona, Magdalena, Yatusevich, Ruslan, Manjunath, Veena Halale, Szewc, Lukasz, Jarmolowski, Artur, Swiezewski, Szymon
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.08.2025; Nature Publishing Group; Nature Portfolio
• Subjects: 38/1; 38/109; 38/15; 38/22; 38/23; 38/32; 38/77; 38/88; 38/90; 38/91; 631/337/384/2568; 631/449/1659; 631/449/2679; Abscisic acid; Abscisic Acid - metabolism; Arabidopsis; Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis - physiology; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Chromatin; Chromatin - genetics; Chromatin - metabolism; Chromosomes; Dormancy; Gene expression; Gene Expression Regulation, Plant; Genomes; Germination; Germination - genetics; High temperature; Homology; Humanities and Social Sciences; multidisciplinary; Mutation; Non-coding RNA; Plant Dormancy - genetics; Polyadenylation; Proteins; Retention; Ribonucleoproteins (small nuclear); RNA polymerase; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Science; Science (multidisciplinary); Seed germination; Seeds; Seeds - genetics; Seeds - metabolism; Signal transduction; Signal Transduction - genetics

Many plant lncRNAs regulate gene expression by binding to chromatin, but how they are retained at the target loci is unclear. We identify a chromatin-localized lncRNA - MUSHER , which activates two parallel regulatory pathways to increase Arabidopsis seed dormancy. MUSHER is upregulated in response...