Quantification of cocaine in ternary mixtures using partial least squares regression applied to Raman and Fourier transform infrared spectroscopy

• Published in: Journal of Raman spectroscopy Vol. 48; no. 12; pp. 1732 - 1743
• Main Authors: Oliveira Penido, Ciro Augusto Fernandes, Pacheco, Marcos Tadeu Tavares, Novotny, Etelvino Henrique, Lednev, Igor K., Silveira, Landulfo
• Format: Journal Article
• Language: English
• Published: Bognor Regis Wiley Subscription Services, Inc 01.12.2017
• Subjects: Adulterants; Caffeine; Cocaine; Correlation coefficient; Correlation coefficients; crack; Differential diagnosis; Drug abuse; Fourier transforms; Infrared spectroscopy; intoxication; Least squares method; Lidocaine; multivariate regression; Narcotics; partial least squares; Poisoning; quantification; Raman spectroscopy; Reagents; Regression analysis; Sodium; Sodium carbonate; Spectra; Spectrum analysis; Substance use; Suicide; Suicides & suicide attempts; Toxic substances; Toxicity; vibrational spectroscopy

The use of chemicals is often related to suicide attempts and acute poisoning, which account for a significant number of hospital admissions. The differential diagnosis of patients exposed to poisoning is intricate and varies according to the substance used. The identification of drugs and drug abus...