Single-cell multi-omics sequencing and its applications in studying the nervous system

• Published in: Biophysics reports Vol. 8; no. 3; pp. 136 - 149
• Main Authors: Chaoyang, Wang, Xiaoying, Fan
• Format: Journal Article
• Language: English
• Published: China Institute of Biophysics 30.06.2022; Biophysics Reports Editorial Office
• Subjects: Biological analysis; Chromatin; DNA methylation; Epigenetics; Gene expression; Heterogeneity; Laboratories; Nervous system; Neurons; Physiology; Proteins; Review; Stem cells; Transcriptomes; Nervous system; Single-cell sequencing; Cell heterogeneity; Multi-omics

Single-cell sequencing has become one of the most powerful and popular techniques in dissecting molecular heterogeneity and modeling the cellular architecture of a biological system. During the past twenty years, the throughput of single-cell sequencing has increased from hundreds of cells to over t...