Immunoexpression of CXCL12 and CXCR4 in sporadic and Gorlin-Goltz syndrome-related odontogenic keratocysts

• Published in: Journal of clinical and experimental dentistry Vol. 14; no. 5; pp. e426 - e432
• Main Authors: de Lima, Wliana-Pontes, Andrade, Allany-de Oliveira, Cavalcante, Roberta-Barroso, Nogueira, Renato-Luiz-Maia, Alves, Pollianna-Muniz, Nonaka, Cassiano-Francisco-Weege, Gordón-Núñez, Manuel-Antonio
• Format: Journal Article
• Language: English
• Published: Spain Medicina Oral S.L 01.05.2022

Differences in the pathogenesis and biological behavior of sporadic and Gorlin-Goltz syndrome-related odontogenic keratocysts (OKCs) have been reported, but the underlying mechanisms are not fully elucidated. Chemokine CXCL12 and its main receptor CXCR4 regulate important events in the pathogenesis...