Bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease: results of six patients

In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were completed before and after surgery in a double-blind fashion under the following six conditions: (a) on medication, (b) off medication, (c) o...

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Published inThe Journal of neuroscience nursing Vol. 35; no. 4; pp. 223 - 231
Main Authors Eriksen, Sharon K, Tuite, Paul J, Maxwell, Robert E, Sullivan, Mary, Low, Walter C, Ebner, Timothy J
Format Journal Article
LanguageEnglish
Published United States Lippincott Williams & Wilkins, WK Health 01.08.2003
American Association of Neurosurgical Nurses
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Abstract In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were completed before and after surgery in a double-blind fashion under the following six conditions: (a) on medication, (b) off medication, (c) on medication/on stimulation, (d) on medication/off stimulation, (e) off medication/on stimulation, and (f) off medication/off stimulation. On average, improvement was noted in all areas including the Unified Parkinson's Disease Rating Scale, Schwab and England Activities of Daily Living Scale, Modified Hoehn and Yahr Staging, and timed tests: In addition, dyskinesia duration and dyskinesia disability were reduced.
AbstractList In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were completed before and after surgery in a double-blind fashion under the following six conditions: (a) on medication, (b) off medication, (c) on medication/on stimulation, (d) on medication/off stimulation, (e) off medication/on stimulation, and (f) off medication/off stimulation. On average, improvement was noted in all areas including the Unified Parkinson's Disease Rating Scale, Schwab and England Activities of Daily Living Scale, Modified Hoehn and Yahr Staging, and timed tests: In addition, dyskinesia duration and dyskinesia disability were reduced.
Audience Professional
Author Tuite, Paul J
Maxwell, Robert E
Low, Walter C
Ebner, Timothy J
Sullivan, Mary
Eriksen, Sharon K
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/12942657$$D View this record in MEDLINE/PubMed
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Snippet In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were...
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StartPage 223
SubjectTerms Activities of Daily Living
Aged
Care and treatment
Case studies
Electric Stimulation Therapy - adverse effects
Electric Stimulation Therapy - methods
Female
Humans
Male
Middle Aged
Neurology
Nurse Practitioners
Nursing
Parkinson Disease - rehabilitation
Parkinson Disease - surgery
Parkinson Disease - therapy
Parkinson's disease
Subthalamic Nucleus - surgery
Treatment Outcome
Title Bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease: results of six patients
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Volume 35
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