Does glucagon like peptide-2 receptor expression have any effect on the development of human colorectal cancer?

• Published in: The Turkish journal of gastroenterology Vol. 22; no. 4; pp. 388 - 394
• Main Authors: BENGI, Goksel, KAYAHAN, Hasan, AKARSU, Mesut, AYSAL, Anil, SAGOL, Ozgul, MERAL, Murat, AKPINAR, Hale
• Format: Journal Article
• Language: English
• Published: Turkey 01.08.2011
• Subjects: Adenocarcinoma - metabolism; Adenocarcinoma - pathology; Adenoma - metabolism; Adenoma - pathology; Adult; Aged; Aged, 80 and over; Colonic Polyps - metabolism; Colonic Polyps - pathology; Colorectal Neoplasms - metabolism; Colorectal Neoplasms - pathology; Female; Glucagon-Like Peptide 2 - metabolism; Glucagon-Like Peptide-2 Receptor; Humans; Immunohistochemistry; Male; Middle Aged; Receptors, Glucagon - metabolism
• ISSN: 1300-4948; 2148-5607; 2148-5607
• DOI: 10.4318/tjg.2011.0243

Glucagon like peptide-2 may play an important role in human colon cancer and polyp development because of its proliferative and antiapopitotic effects especially in colon. In this study, we investigated the role of human glucagon like peptide and it's receptor in development of human colorectal...