The neurotoxic mechanism of Jack Bean Urease in insects involves the interplay between octopaminergic and dopaminergic pathways

• Published in: Pesticide biochemistry and physiology Vol. 189; p. 105290
• Main Authors: Barreto, Yuri Correia, Oliveira, Raquel Soares, Borges, Bruna Trindade, Rosa, Maria Eduarda, Zanatta, Ana Paula, de Almeida, Carlos Gabriel Moreira, Vinadé, Lúcia, Carlini, Celia Regina, Belo, Cháriston André Dal
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2023
• Subjects: Animals; Cockroaches; Jack bean urease; Mianserin - pharmacology; Monoaminergic pathways; Natural insecticides; Nauphoeta cinerea cockroaches; Neurolocomotor disturbance; Phentolamine - pharmacology; Reserpine - pharmacology; Urease - pharmacology; Nauphoeta cinerea cockroaches; Neurolocomotor disturbance; Monoaminergic pathways; Natural insecticides; Jack bean urease

In the last decades, the entomotoxicity of JBU and its derived peptides became an object of study, due mainly to the ubiquitous interaction of these compounds with different species of insects and their potential as natural insecticides. In this work, we investigated the neurotoxic effects of JBU in...