Dynamic Modelling and Optimisation of the Batch Enzymatic Synthesis of Amoxicillin - Cuthbertson, Andrew B.; Rodman, Alistair D.; Diab, Samir; Gerogiorgis, Dimitrios I. (Processes, 2019)
Keywords: Amides; Aminopenicillanic acid; Amoxicillin; Antibiotics; Batch processes; Design; Dynamic models; Enzymatic synthesis; Enzymes; Modelling; Operating temperature; Optimal control; Optimization; Parameter estimation; Pharmaceuticals; Product specifications; Raw materials; Simulation; Substrates; Temperature; Urinary tract; β-Lactam antibiotics