Recurrent bladder urothelial carcinoma complicated with primary bladder large cell neuroendocrine carcinoma: a case report and literature review

To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). A clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The...

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Published inFrontiers in oncology Vol. 14; p. 1369649
Main Authors Cui, Jiarui, Zhao, Qing, Yu, Chunhong, Ma, Pengfei, Li, Shoubin
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 02.08.2024
Subjects
bladder tumor
diagnosis
LCNEC
prognosis
treatment
treatment
diagnosis
LCNEC
bladder tumor
prognosis
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Abstract To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). A clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature. The female patient was admitted to hospital for "more than 4 years after TURBT and intermittent hematuria for more than 2 years". She was diagnosed as recurrent bladder cancer and underwent "radical cystotomy + hysterectomy". The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up. Bladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.
AbstractList To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). A clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature. The female patient was admitted to hospital for "more than 4 years after TURBT and intermittent hematuria for more than 2 years". She was diagnosed as recurrent bladder cancer and underwent "radical cystotomy + hysterectomy". The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up. Bladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.
Objective To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). Methods A clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature. Results The female patient was admitted to hospital for “more than 4 years after TURBT and intermittent hematuria for more than 2 years”. She was diagnosed as recurrent bladder cancer and underwent “radical cystotomy + hysterectomy”. The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up. Conclusion Bladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.
ObjectiveTo improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC).MethodsA clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature.ResultsThe female patient was admitted to hospital for “more than 4 years after TURBT and intermittent hematuria for more than 2 years”. She was diagnosed as recurrent bladder cancer and underwent “radical cystotomy + hysterectomy”. The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up.ConclusionBladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.
To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC).ObjectiveTo improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC).A clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature.MethodsA clinical case of bladder LCNEC admitted to our hospital was reported. The epidemiology, prognosis, diagnosis and treatment methods of large cell neuroendocrine carcinoma were reviewed. The diagnosis and treatment status and prognosis were discussed based on the literature.The female patient was admitted to hospital for "more than 4 years after TURBT and intermittent hematuria for more than 2 years". She was diagnosed as recurrent bladder cancer and underwent "radical cystotomy + hysterectomy". The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up.ResultsThe female patient was admitted to hospital for "more than 4 years after TURBT and intermittent hematuria for more than 2 years". She was diagnosed as recurrent bladder cancer and underwent "radical cystotomy + hysterectomy". The postoperative pathological findings were high-grade urothelial carcinoma of the bladder neck and large cell neuroendocrine carcinoma of the bladder. The patient recovered well after surgery, but refused radiotherapy and chemotherapy and is still under close follow-up.Bladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.ConclusionBladder LCNEC is clinically rare, has unique pathological features, is more aggressive than traditional urothelial carcinoma, and has a poor prognosis. Surgery, chemotherapy and radiotherapy should be combined with multi-mode treatment.
Author Zhao, Qing
Cui, Jiarui
Ma, Pengfei
Yu, Chunhong
Li, Shoubin
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Cites_doi 10.1016/j.clgc.2019.10.016
10.1016/j.ejso.2020.05.006
10.1155/2017/4812453
10.1111/bju.16296
10.1001/jamaoncol.2017.0589
10.1016/j.clgc.2019.11.014
10.1007/s00261-012-9971-6
10.3389/fonc.2024.1341794
10.1038/modpathol.2011.569
10.1016/j.eucr.2023.102347
10.1038/s41585-020-00379-4
10.15386/cjmed-673
10.3389/fonc.2020.01291
10.1016/j.clgc.2015.03.005
10.1097/PAS.0000000000001740
10.1111/his.13719
10.3390/ijms222111547
10.1097/PAT.0000000000000301
10.2147/CMAR.S175286
10.4081/rt.2014.5043
10.3389/fonc.2024.1337997
10.1016/j.humpath.2020.01.004
10.1111/j.1440-1827.2006.02031.x
10.21873/anticanres.14213
10.1038/s41467-021-24812-3
10.1111/bju.15984
10.3390/jcm12247715
10.21873/anticanres.11850
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diagnosis
LCNEC
bladder tumor
prognosis
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References Bhatt (B22) 2014; 6
Dasari (B4) 2017; 3
Ghervan (B7) 2017; 90
Zhou (B16) 2017; 37
Nguyen (B17) 2024; 14
Mahmoudnejad (B27) 2023; 47
Claps (B31) 2023; 132
Luzzago (B24) 2019; 18
Wang (B12) 2021; 45
Martín (B15) 2011; 64
(B5) 2022
Gupta (B21) 2015; 47
Sroussi (B25) 2019; 18
Sun (B2) 2024; 14
Deuker (B26) 2020; 47
Williamson (B8) 2011; 24
Stumpo (B10) 2023; 12
Lee (B14) 2006; 56
van Riet (B28) 2021; 12
Boyer (B9) 2013; 38
Abenoza (B6) 1986; 110
Pederzoli (B29) 2020; 17
Niu (B19) 2018; 10
Oshiro (B18) 2013; 6
Dowd (B23) 2017; 2017
Wucherpfennig (B30) 2021; 22
Matsuda (B32) 2024; 134
Xia (B20) 2020; 10
Sanguedolce (B3) 2020; 40
Park (B11) 2019; 74
Radović (B1) 2015; 13
Akgul (B13) 2020; 98
References_xml – volume: 18
  start-page: 117
  year: 2019
  ident: B24
  article-title: Survival after partial cystectomy for variant histology bladder cancer compared with urothelial carcinoma: A population-based study
  publication-title: Clin Genitourin Canc
  doi: 10.1016/j.clgc.2019.10.016
  contributor:
    fullname: Luzzago
– volume: 47
  year: 2020
  ident: B26
  article-title: Radical cystectomy improves survival in patients with stage T1 squamous cell carcinoma and neuroendocrine carcinoma of the urinary bladder
  publication-title: Ejso-Eur J Surg Onc
  doi: 10.1016/j.ejso.2020.05.006
  contributor:
    fullname: Deuker
– volume: 2017
  year: 2017
  ident: B23
  article-title: Rare occurrence of a poorly differentiated neuroendocrine tumor of the bladder
  publication-title: Case Rep Med
  doi: 10.1155/2017/4812453
  contributor:
    fullname: Dowd
– volume: 64
  year: 2011
  ident: B15
  article-title: Large cell neuroendocrine carcinoma of the urinary bladder. Bibliographic review
  publication-title: Arch Esp Urol
  contributor:
    fullname: Martín
– volume: 134
  year: 2024
  ident: B32
  article-title: Prognostic impact of histological discordance between transurethral resection and radical cystectomy
  publication-title: Bju Int
  doi: 10.1111/bju.16296
  contributor:
    fullname: Matsuda
– volume: 3
  year: 2017
  ident: B4
  article-title: Trends in the incidence, prevalence, and survival outcomes in patients with neuroendocrine tumors in the United States
  publication-title: JAMA Oncol
  doi: 10.1001/jamaoncol.2017.0589
  contributor:
    fullname: Dasari
– volume: 18
  start-page: 295
  year: 2019
  ident: B25
  article-title: Neuroendocrine carcinoma of the urinary bladder: A large, retrospective study from the french genito-urinary tumor group
  publication-title: Clin Genitourin Canc
  doi: 10.1016/j.clgc.2019.11.014
  contributor:
    fullname: Sroussi
– volume: 38
  year: 2013
  ident: B9
  article-title: Neuroendocrine carcinoma of the urinary bladder: a retrospective study of CT findings
  publication-title: Abdom Imaging
  doi: 10.1007/s00261-012-9971-6
  contributor:
    fullname: Boyer
– volume: 14
  year: 2024
  ident: B17
  article-title: A systematic review of primary large cell neuroendocrine carcinoma of the prostate
  publication-title: Front Oncol
  doi: 10.3389/fonc.2024.1341794
  contributor:
    fullname: Nguyen
– volume: 24
  year: 2011
  ident: B8
  article-title: ERG-TMPRSS2 rearrangement is shared by concurrent prostatic adenocarcinoma and prostatic small cell carcinoma and absent in small cell carcinoma of the urinary bladder: evidence supporting monoclonal origin
  publication-title: Modern Pathol
  doi: 10.1038/modpathol.2011.569
  contributor:
    fullname: Williamson
– volume: 47
  year: 2023
  ident: B27
  article-title: Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
  publication-title: Urol Case Rep
  doi: 10.1016/j.eucr.2023.102347
  contributor:
    fullname: Mahmoudnejad
– volume: 17
  year: 2020
  ident: B29
  article-title: Targetable gene fusions and aberrations in genitourinary oncology
  publication-title: Nat Rev Urol
  doi: 10.1038/s41585-020-00379-4
  contributor:
    fullname: Pederzoli
– volume: 90
  year: 2017
  ident: B7
  article-title: Small-cell carcinoma of the urinary bladder: where do we stand
  publication-title: Clujul Med
  doi: 10.15386/cjmed-673
  contributor:
    fullname: Ghervan
– volume: 10
  year: 2020
  ident: B20
  article-title: Clinical characteristics, treatment strategy, and outcomes of primary large cell neuroendocrine carcinoma of the bladder: A case report and systematic review of the literature
  publication-title: Front Oncol
  doi: 10.3389/fonc.2020.01291
  contributor:
    fullname: Xia
– volume: 13
  year: 2015
  ident: B1
  article-title: Primary “Pure” Large cell neuroendocrine carcinoma of the urinary bladder: A case report and review of the literature
  publication-title: Clin Genitourin Canc
  doi: 10.1016/j.clgc.2015.03.005
  contributor:
    fullname: Radović
– volume: 45
  year: 2021
  ident: B12
  article-title: Urinary large cell neuroendocrine carcinoma: A clinicopathologic analysis of 22 cases
  publication-title: Am J Surg Pathol
  doi: 10.1097/PAS.0000000000001740
  contributor:
    fullname: Wang
– volume: 74
  start-page: 97
  year: 2019
  ident: B11
  article-title: Non-urothelial carcinomas of the bladder
  publication-title: Histopathology
  doi: 10.1111/his.13719
  contributor:
    fullname: Park
– volume: 6
  year: 2013
  ident: B18
  article-title: Primary large cell neuroendocrine carcinoma of the ureter
  publication-title: Int J Clin Exp Pathol
  contributor:
    fullname: Oshiro
– volume: 22
  year: 2021
  ident: B30
  article-title: Evaluation of therapeutic targets in histological subtypes of bladder cancer
  publication-title: Int J Mol Sci
  doi: 10.3390/ijms222111547
  contributor:
    fullname: Wucherpfennig
– volume: 47
  year: 2015
  ident: B21
  article-title: High grade neuroendocrine carcinoma of the urinary bladder treated by radical cystectomy: a series of small cell, mixed neuroendocrine and large cell neuroendocrine carcinoma
  publication-title: Pathology
  doi: 10.1097/PAT.0000000000000301
  contributor:
    fullname: Gupta
– volume: 10
  year: 2018
  ident: B19
  article-title: Clinicopathological characteristics and survival outcomes of bladder neuroendocrine carcinomas: a population-based study
  publication-title: Cancer Manag Res
  doi: 10.2147/CMAR.S175286
  contributor:
    fullname: Niu
– volume-title: WHO classification of tumours series
  year: 2022
  ident: B5
  article-title: Urinary and male genital tumours
– volume: 6
  year: 2014
  ident: B22
  article-title: Risk factors, therapy and survival outcomes of small cell and large cell neuroendocrine carcinoma of urinary bladder
  publication-title: Rare Tumors
  doi: 10.4081/rt.2014.5043
  contributor:
    fullname: Bhatt
– volume: 14
  year: 2024
  ident: B2
  article-title: Primary pure large cell neuroendocrine carcinoma of the urinary bladder: a case report and literature review
  publication-title: Front Oncol
  doi: 10.3389/fonc.2024.1337997
  contributor:
    fullname: Sun
– volume: 98
  start-page: 32
  year: 2020
  ident: B13
  article-title: The applicability and utility of immunohistochemical biomarkers in bladder pathology
  publication-title: Hum Pathol
  doi: 10.1016/j.humpath.2020.01.004
  contributor:
    fullname: Akgul
– volume: 56
  year: 2006
  ident: B14
  article-title: Primary large cell neuroendocrine carcinoma of the urinary bladder
  publication-title: Pathol Int
  doi: 10.1111/j.1440-1827.2006.02031.x
  contributor:
    fullname: Lee
– volume: 40
  year: 2020
  ident: B3
  article-title: Urinary tract large cell neuroendocrine carcinoma: diagnostic, prognostic and therapeutic issues
  publication-title: Anticancer Res
  doi: 10.21873/anticanres.14213
  contributor:
    fullname: Sanguedolce
– volume: 12
  start-page: 4612
  year: 2021
  ident: B28
  article-title: The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets
  publication-title: Nat Commun
  doi: 10.1038/s41467-021-24812-3
  contributor:
    fullname: van Riet
– volume: 132
  year: 2023
  ident: B31
  article-title: Prognostic impact of variant histologies in urothelial bladder cancer treated with radical cystectomy
  publication-title: Bju Int
  doi: 10.1111/bju.15984
  contributor:
    fullname: Claps
– volume: 12
  year: 2023
  ident: B10
  article-title: Extrapulmonary neuroendocrine carcinomas: current management and future perspectives
  publication-title: J Clin Med
  doi: 10.3390/jcm12247715
  contributor:
    fullname: Stumpo
– volume: 37
  year: 2017
  ident: B16
  article-title: Analysis of clinicopathological features and prognostic factors in 39 cases of bladder neuroendocrine carcinoma
  publication-title: Anticancer Res
  doi: 10.21873/anticanres.11850
  contributor:
    fullname: Zhou
– volume: 110
  year: 1986
  ident: B6
  article-title: Adenocarcinoma with neuroendocrine differentiation of the urinary bladder. Clinicopathologic, immunohistochemical, and ultrastructural study
  publication-title: Arch Pathol Lab Med
  contributor:
    fullname: Abenoza
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Snippet To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). A clinical case of bladder LCNEC admitted to our...
Objective To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC). Methods A clinical case of bladder...
To improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC).ObjectiveTo improve the understanding, diagnosis...
ObjectiveTo improve the understanding, diagnosis and treatment of bladder large cell neuroendocrine carcinoma (LCNEC).MethodsA clinical case of bladder LCNEC...
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SubjectTerms bladder tumor
diagnosis
LCNEC
prognosis
treatment
Title Recurrent bladder urothelial carcinoma complicated with primary bladder large cell neuroendocrine carcinoma: a case report and literature review
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