Phenobarbital as Anticonvulsant Prophylaxis in Patients With Traumatic Brain Injury at Risk for Alcohol Withdrawal Syndrome

• Published in: Journal of pharmacy practice Vol. 37; no. 3; p. 665
• Main Authors: McGinnis, Cory B, Wang, Fajun, Chiappelli, Abby L, Okonkwo, David O, Darby, Joseph M
• Format: Journal Article
• Language: English
• Published: United States 01.06.2024
• Subjects: traumatic brain injury; phenobarbital; alcohol withdrawal; post-traumatic seizures

Anticonvulsant prophylaxis (ACP) for early post-traumatic seizures (PTS) is recommended in patients with traumatic brain injury (TBI). Phenobarbital (PB) may be used to prevent alcohol withdrawal syndrome (AWS) in at-risk patients. The dual-purpose use of PB in the TBI population would allow for con...