Longitudinal impact of stressful life events on HIV-related risk and psychosocial problems among MSM in Chennai and Mumbai, India

Studies show that stressful life events (SLE) (e.g., discrimination, financial problems) can lead to psychosocial problems and exacerbate condomless anal sex (CAS) without protection via pre-exposure prophylaxis (PrEP) among men who have sex with men. However, few studies have examined this relation...

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Published inInternational journal of STD & AIDS Vol. 34; no. 6; p. 416
Main Authors Lodge Ii, William, Biello, Katie, Thomas, Beena, Rawat, Shruta, Baruah, Dicky, Dange, Alpana, Anand, Vivek, Swaminathan, Soumya, Kumar, Senthil, Balu, Vinoth, Menon, Sunil, O'Cleirigh, Conall, Mayer, Kenneth H, Safren, Steven A, Mimiaga, Matthew J
Format Journal Article
LanguageEnglish
Published England 01.05.2023
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Abstract Studies show that stressful life events (SLE) (e.g., discrimination, financial problems) can lead to psychosocial problems and exacerbate condomless anal sex (CAS) without protection via pre-exposure prophylaxis (PrEP) among men who have sex with men. However, few studies have examined this relationship among men who have sex with men in India, and none have examined this longitudinally. As a part of an HIV-prevention intervention, 608 MSM from Chennai and Mumbai, India, completed behavioral surveys at baseline, 4, 8, and 12 months. We used longitudinal generalized estimating equations (GEE) modeling to examine the relationship between SLE and its severity and subsequent psychosocial problems, CAS, and history of diagnosed sexually transmitted infection (STI). All models are adjusted for age, sexual identity, intervention arm, human immunodeficiency virus status, and recruitment city. The number of SLE and their corresponding perceived impact score remained consistent at each time point. In multivariable GEE models, the number of SLE was predictive of CAS, depression, and harmful drinking. Similarly, the ratio of the impact of SLE was predictive of CAS, depression, and diagnosed STI. However, harmful drinking was not predictive in this model. These findings provide evidence that can inform future interventions, which can be used to enhance self-acceptance, coping skills, and other forms of resiliency.
AbstractList Studies show that stressful life events (SLE) (e.g., discrimination, financial problems) can lead to psychosocial problems and exacerbate condomless anal sex (CAS) without protection via pre-exposure prophylaxis (PrEP) among men who have sex with men. However, few studies have examined this relationship among men who have sex with men in India, and none have examined this longitudinally. As a part of an HIV-prevention intervention, 608 MSM from Chennai and Mumbai, India, completed behavioral surveys at baseline, 4, 8, and 12 months. We used longitudinal generalized estimating equations (GEE) modeling to examine the relationship between SLE and its severity and subsequent psychosocial problems, CAS, and history of diagnosed sexually transmitted infection (STI). All models are adjusted for age, sexual identity, intervention arm, human immunodeficiency virus status, and recruitment city. The number of SLE and their corresponding perceived impact score remained consistent at each time point. In multivariable GEE models, the number of SLE was predictive of CAS, depression, and harmful drinking. Similarly, the ratio of the impact of SLE was predictive of CAS, depression, and diagnosed STI. However, harmful drinking was not predictive in this model. These findings provide evidence that can inform future interventions, which can be used to enhance self-acceptance, coping skills, and other forms of resiliency.
Author Anand, Vivek
Dange, Alpana
Balu, Vinoth
Baruah, Dicky
Kumar, Senthil
Biello, Katie
Rawat, Shruta
Mayer, Kenneth H
O'Cleirigh, Conall
Mimiaga, Matthew J
Thomas, Beena
Swaminathan, Soumya
Safren, Steven A
Lodge Ii, William
Menon, Sunil
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  organization: National Institute for Research in Tuberculosis (NIRT), Chennai, India
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  organization: Harvard Medical School, Boston, MA, USA
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  surname: Mayer
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  organization: Harvard Medical School, Boston, MA, USA
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  givenname: Steven A
  orcidid: 0000-0002-0121-0806
  surname: Safren
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  fullname: Mimiaga, Matthew J
  organization: Department of Psychiatry & Biobehavioral Sciences, UCLA David Geffen School of Medicine, Los Angeles, CA, USA
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Issue 6
Keywords Indian subcontinent
men who have sex with men
mental health
Human immunodeficiency virus (HIV)
India
Language English
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Snippet Studies show that stressful life events (SLE) (e.g., discrimination, financial problems) can lead to psychosocial problems and exacerbate condomless anal sex...
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StartPage 416
SubjectTerms Alcoholism
HIV Infections - prevention & control
Homosexuality, Male
Humans
India - epidemiology
Male
Pre-Exposure Prophylaxis
Sexual and Gender Minorities
Sexual Behavior
Sexually Transmitted Diseases - epidemiology
Sexually Transmitted Diseases - prevention & control
Stress, Psychological
Title Longitudinal impact of stressful life events on HIV-related risk and psychosocial problems among MSM in Chennai and Mumbai, India
URI https://www.ncbi.nlm.nih.gov/pubmed/36825555
Volume 34
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