Micro-RNA in Cholangiocarcinoma: Implications for Diagnosis, Prognosis, and Therapy

• Published in: Journal of Molecular Pathology Vol. 3; no. 2; pp. 88 - 103
• Main Authors: Barbato, Anna, Piscopo, Fabiola, Salati, Massimiliano, Reggiani-Bonetti, Luca, Franco, Brunella, Carotenuto, Pietro
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.06.2022
• Subjects: Antitumor agents; Apoptosis; bile duct cancer; Biomarkers; Carcinogenesis; Cell death; Cholangiocarcinoma; Clinical trials; Diagnosis; Gene expression; Genomes; Kinases; Metastases; microRNA; MicroRNAs; miRNA; Next-generation sequencing; Non-coding RNA; precision medicine; Prognosis; Ribonucleic acid; RNA; Solid tumors; Transcriptomes

Bile-duct cancers (BDC) are a group of solid tumors arising from the biliary tree. Despite their classification as rare cancers, the incidence of BDC is increasing worldwide. Poor prognosis is a common feature of this type of cancer and is mainly determined by the following factors: late diagnosis,...