DNA Methylation of BRCA1, BRCA2, and TP53 Promoters as Biomarker for the Early Diagnosis of Simian Virus 40-Related Breast Carcinoma

• Published in: Indian journal of gynecologic oncology Vol. 22; no. 1
• Main Authors: Sosse, Soukayna Alaoui, Tadlaoui, Kaoutar Anouar, Saif, Imane, Benhassou, Mustapha, Elkarroumi, Mohamed, Ennaji, Moulay Mustapha
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.03.2024
• Subjects: Medicine; Medicine & Public Health; Oncology; Original Article; Surgical Oncology; Methylation; Viral infection; Breast cancer

Background Breast cancer (BC) is one of the major causes of death among women. Multiple risk factors are associated with the BC development, such as viral infections including simian virus 40 ( SV40 ), genetic alterations, and epigenetics due to aberrant methylation of tumor suppressor genes. Object...