Depression Is Associated With High Levels of C-Reactive Protein and Low Levels of Fractional Exhaled Nitric Oxide: Results From the 2007-2012 National Health and Nutrition Examination Surveys

• Published in: The journal of clinical psychiatry Vol. 77; no. 12; p. 1666
• Main Authors: Cepeda, M Soledad, Stang, Paul, Makadia, Rupa
• Format: Journal Article
• Language: English
• Published: United States 01.12.2016
• Subjects: Adult; Aged; Aged, 80 and over; Breath Tests; C-Reactive Protein - metabolism; Cross-Sectional Studies; Depression - blood; Depression - epidemiology; Depression - metabolism; Female; Health Surveys; Humans; Inflammation - blood; Inflammation - epidemiology; Inflammation - metabolism; Male; Middle Aged; Nitric Oxide - metabolism; Nutrition Surveys; United States - epidemiology; Young Adult

Major depressive disorder may be due to psychoneuroimmunological dysfunction, as studies have documented increased levels of a variety of inflammatory mediators in depressed subjects. Nitric oxide (NO) is marker of inflammation, and fractional exhaled NO (FeNO) is a marker of airway inflammation. Pl...