Trials of transmission imaging using clinically used Ir-192 source for high-dose-rate brachytherapy

In high-dose-rate (HDR) brachytherapy, verification of an Ir-192 source's position during treatment is required. One of the methods for this used a high-energy pinhole gamma camera to image the position of the source, but the absolute position of the source cannot be measured. To confirm the ab...

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Published inJournal of instrumentation Vol. 17; no. 6; p. T06009
Main Authors Nagata, J., Yamamoto, S., Nakanishi, K., Noguchi, Y., Okudaira, K., Kataoka, J.
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.06.2022
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ISSN1748-0221
1748-0221
DOI10.1088/1748-0221/17/06/T06009

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Abstract In high-dose-rate (HDR) brachytherapy, verification of an Ir-192 source's position during treatment is required. One of the methods for this used a high-energy pinhole gamma camera to image the position of the source, but the absolute position of the source cannot be measured. To confirm the absolute position, it will be useful to acquire the transmission image of a subject in addition to the gamma photon image at the same time without using an additional X-ray system. To measure the transmission images, we tried to use the high-energy gamma photons emitted from the Ir-192 source used for the therapy. We developed a high-energy gamma photon imaging system composed of 1-mm-thick Pr doped Gd 2 O 2 S (GOS), a surface mirror, and a cooled charge-coupled device (CCD) camera. The developed imaging system achieved transmission imaging of high-energy gamma photons by transporting the Ir-192 source in front of the imaging system. The spatial resolution of the imaging system was better than 2.4 mm FWHM with and without a 10-cm-thick acrylic block set between the imaging system and the source. Moderate spatial resolution and contrast images of phantoms were obtained with the system. For the dynamic imaging mode, continuous images of the phantoms were measured with 1-sec intervals. There was no observable difference in the transmission images by the movement of the Ir-192 source. Transmission imaging of subjects using an Ir-192 source for HDR brachytherapy could be achieved using our developed imaging system. The system offers a new method to measure the real-time transmission images of the subject during HDR brachytherapy.
AbstractList In high-dose-rate (HDR) brachytherapy, verification of an Ir-192 source's position during treatment is required. One of the methods for this used a high-energy pinhole gamma camera to image the position of the source, but the absolute position of the source cannot be measured. To confirm the absolute position, it will be useful to acquire the transmission image of a subject in addition to the gamma photon image at the same time without using an additional X-ray system. To measure the transmission images, we tried to use the high-energy gamma photons emitted from the Ir-192 source used for the therapy. We developed a high-energy gamma photon imaging system composed of 1-mm-thick Pr doped Gd 2 O 2 S (GOS), a surface mirror, and a cooled charge-coupled device (CCD) camera. The developed imaging system achieved transmission imaging of high-energy gamma photons by transporting the Ir-192 source in front of the imaging system. The spatial resolution of the imaging system was better than 2.4 mm FWHM with and without a 10-cm-thick acrylic block set between the imaging system and the source. Moderate spatial resolution and contrast images of phantoms were obtained with the system. For the dynamic imaging mode, continuous images of the phantoms were measured with 1-sec intervals. There was no observable difference in the transmission images by the movement of the Ir-192 source. Transmission imaging of subjects using an Ir-192 source for HDR brachytherapy could be achieved using our developed imaging system. The system offers a new method to measure the real-time transmission images of the subject during HDR brachytherapy.
In high-dose-rate (HDR) brachytherapy, verification of anIr-192 source's position during treatment is required. One of themethods for this used a high-energy pinhole gamma camera to imagethe position of the source, but the absolute position of the sourcecannot be measured. To confirm the absolute position, it will beuseful to acquire the transmission image of a subject in addition tothe gamma photon image at the same time without using an additionalX-ray system. To measure the transmission images, we tried to usethe high-energy gamma photons emitted from the Ir-192 source usedfor the therapy. We developed a high-energy gamma photon imagingsystem composed of 1-mm-thick Pr doped Gd2O2S (GOS), asurface mirror, and a cooled charge-coupled device (CCD) camera. Thedeveloped imaging system achieved transmission imaging ofhigh-energy gamma photons by transporting the Ir-192 source in frontof the imaging system. The spatial resolution of the imaging systemwas better than 2.4 mm FWHM with and without a 10-cm-thick acrylicblock set between the imaging system and the source. Moderatespatial resolution and contrast images of phantoms were obtainedwith the system. For the dynamic imaging mode, continuous images ofthe phantoms were measured with 1-sec intervals. There was noobservable difference in the transmission images by the movement ofthe Ir-192 source. Transmission imaging of subjects using an Ir-192source for HDR brachytherapy could be achieved using our developedimaging system. The system offers a new method to measure thereal-time transmission images of the subject during HDRbrachytherapy.
Author Okudaira, K.
Nagata, J.
Noguchi, Y.
Kataoka, J.
Yamamoto, S.
Nakanishi, K.
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Snippet In high-dose-rate (HDR) brachytherapy, verification of an Ir-192 source's position during treatment is required. One of the methods for this used a high-energy...
In high-dose-rate (HDR) brachytherapy, verification of anIr-192 source's position during treatment is required. One of themethods for this used a high-energy...
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StartPage T06009
SubjectTerms Cameras
Charge coupled devices
Image acquisition
Image contrast
Image transmission
Instrumentation for gamma-electron therapy
Photons
Pinholes
Position measurement
Radiation dosage
Radiation therapy
Radiotherapy concepts
Scintigraphy and whole-body imaging
Spatial resolution
Time measurement
X-ray radiography and digital radiography (DR)
Title Trials of transmission imaging using clinically used Ir-192 source for high-dose-rate brachytherapy
URI https://iopscience.iop.org/article/10.1088/1748-0221/17/06/T06009
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