Synthesis of cyclic α-1,4-oligo- N -acetylglucosamine ‘cyclokasaodorin’ via a one-pot electrochemical polyglycosylation–isomerization–cyclization process

• Published in: Chemical communications (Cambridge, England) Vol. 58; no. 57; pp. 7948 - 7951
• Main Authors: Endo, Hirofumi, Ochi, Masaharu, Rahman, Md Azadur, Hamada, Tomoaki, Kawano, Takahiro, Nokami, Toshiki
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 14.07.2022; Royal Society of Chemistry
• Subjects: Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; electrochemistry; electrosynthesis; glycosylation; Isomerization; N-acetylglucosamine; Oligosaccharides; Physical Sciences; Science & Technology; GLYCOSYLATION

Electrochemical synthesis of unnatural cyclic oligosaccharides composed of N -acetylglucosamine with α-1,4-glycosidic linkages has been accomplished. A thioglycoside monomer equipped with the 2,3-oxazolidinone protecting group was used to prepare linear oligosaccharides by electrochemical polyglycos...