Near-infrared light-activatable upconversion nanoparticle/curcumin hybrid nanodrug: a potent strategy to induce the differentiation and elimination of glioma stem cells

• Published in: Advanced composites and hybrid materials Vol. 7; no. 3
• Main Authors: Jing, Guoxin, Li, Youyuan, Sun, Feiyue, Liu, Qiang, Du, Ai, Wang, Hong, Niu, Jintong, Lu, Jialu, Qian, Yechang, Wang, Shilong
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2024
• Subjects: Ceramics; Chemistry and Materials Science; Composites; Glass; Materials Engineering; Materials Science; Natural Materials; Polymer Sciences; Glioma stem cells; Curcumin; Photodynamic therapy; Photoswitch; Upconversion nanoparticles

Glioma stem cells (GSCs) are major contributors to the recurrence and drug resistance of glioblastoma (GBM) and are therefore a key target for GBM treatment. However, due to the therapeutic resistance of GSCs, innovative and efficient clinical treatment tools to eliminate GSCs are urgently needed. P...