Approximate Inferences for Nonlinear Mixed Effects Models with Scale Mixtures of Skew-Normal Distributions

• Published in: Journal of statistical theory and practice Vol. 15; no. 3
• Main Authors: Schumacher, Fernanda L., Dey, Dipak K., Lachos, Victor H.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.09.2021
• Subjects: Celebrating the Centenary of Professor C. R. Rao; Mathematics and Statistics; Original Article; Probability Theory and Stochastic Processes; Statistical Theory and Methods; Statistics; Approximate likelihood; Nonlinear mixed effects models; Scale mixtures of skew-normal distributions; EM-algorithm; Linearization

Nonlinear mixed effects models have received a great deal of attention in the statistical literature in recent years because of their flexibility in handling longitudinal studies, including human immunodeficiency virus viral dynamics, pharmacokinetic analyses, and studies of growth and decay. A stan...