Striato‐cortical connections in Parkinson's and Alzheimer's diseases: Relation to cognition

• Published in: Movement disorders Vol. 32; no. 6; pp. 917 - 922
• Main Authors: Anderkova, Lubomira, Barton, Marek, Rektorova, Irena
• Format: Journal Article
• Language: English
• Published: United States 01.06.2017
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - complications; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - physiopathology; Alzheimer's disease; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - physiopathology; cognition; Cognitive Dysfunction - diagnostic imaging; Cognitive Dysfunction - etiology; Cognitive Dysfunction - physiopathology; Connectome - methods; Corpus Striatum - diagnostic imaging; Corpus Striatum - physiopathology; Executive Function - physiology; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease - complications; Parkinson Disease - diagnostic imaging; Parkinson Disease - physiopathology; Parkinson's disease; resting state functional connectivity; striatum; resting state functional connectivity; Parkinson's disease; cognition; striatum; Alzheimer's disease

ABSTRACT Background: Functional connectivity is abnormal in PD and in early Alzheimer's disease. Objectives: The objective of this study was to evaluate resting‐state striato‐cortical connectivity in PD and Alzheimer's disease and assess their relation to cognitive outcomes. Groups with mi...