ETC-1002, A MODULATOR OF ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE AND ADENOSINE TRIPHOSPHATE-CITRATE LYASE, WAS SAFE AND REDUCED LOW-DENSITY LIPOPROTEIN-CHOLESTEROL IN HEALTHY VOLUNTEERS
Methods Multiple ascending doses of ETC-1002 were evaluated in 56 healthy subjects, some with mildly elevated low density lipoprotein-cholesterol (LDL-C; >100 mg/dL), in two Phase 1, randomized, double-blind (sponsor open), placebo (PBO)-controlled studies.
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| Published in | Journal of the American College of Cardiology Vol. 61; no. 10; p. E1463 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Elsevier Inc
12.03.2013
Elsevier Limited |
| Subjects | |
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| Abstract | Methods Multiple ascending doses of ETC-1002 were evaluated in 56 healthy subjects, some with mildly elevated low density lipoprotein-cholesterol (LDL-C; >100 mg/dL), in two Phase 1, randomized, double-blind (sponsor open), placebo (PBO)-controlled studies. |
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| AbstractList | Methods Multiple ascending doses of ETC-1002 were evaluated in 56 healthy subjects, some with mildly elevated low density lipoprotein-cholesterol (LDL-C; >100 mg/dL), in two Phase 1, randomized, double-blind (sponsor open), placebo (PBO)-controlled studies. |
| Author | Milad, Mark Vanderlugt, James DiCarlo, Lorenzo Rosenberg, Noah MacDougall, Diane Newton, Roger Margulies, Janice |
| Author_xml | – sequence: 1 givenname: Diane surname: MacDougall fullname: MacDougall, Diane – sequence: 2 givenname: James surname: Vanderlugt fullname: Vanderlugt, James – sequence: 3 givenname: Noah surname: Rosenberg fullname: Rosenberg, Noah – sequence: 4 givenname: Lorenzo surname: DiCarlo fullname: DiCarlo, Lorenzo – sequence: 5 givenname: Mark surname: Milad fullname: Milad, Mark – sequence: 6 givenname: Janice surname: Margulies fullname: Margulies, Janice – sequence: 7 givenname: Roger surname: Newton fullname: Newton, Roger |
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| Copyright | 2013 American College of Cardiology Foundation American College of Cardiology Foundation Copyright Elsevier Limited Mar 12, 2013 |
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| Snippet | Methods Multiple ascending doses of ETC-1002 were evaluated in 56 healthy subjects, some with mildly elevated low density lipoprotein-cholesterol (LDL-C; >100... |
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| Title | ETC-1002, A MODULATOR OF ADENOSINE MONOPHOSPHATE-ACTIVATED PROTEIN KINASE AND ADENOSINE TRIPHOSPHATE-CITRATE LYASE, WAS SAFE AND REDUCED LOW-DENSITY LIPOPROTEIN-CHOLESTEROL IN HEALTHY VOLUNTEERS |
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