A COMPARATIVE EVALUATION OF LOCAL ANESTHETIC EFFECT BETWEEN LIGNOCAINE AND LIGNOCAINE ADMINISTERED WITH EPINEPHRINE IN HEALTHY CHILDREN

• Published in: Acta biochimica Polonica Vol. 66; no. 3; p. 285
• Main Authors: Zhou, Yan, Qiu, Jing
• Format: Journal Article
• Language: English
• Published: Poland 15.07.2019
• Subjects: Abdomen, Acute - surgery; Anesthetics, Local - administration & dosage; Anesthetics, Local - therapeutic use; Child; Child, Preschool; Drug Carriers - chemistry; Drug Combinations; Drug Compounding - methods; Drug Synergism; Epinephrine - administration & dosage; Epinephrine - therapeutic use; Female; Humans; Hydrocortisone - blood; Lidocaine - administration & dosage; Lidocaine - therapeutic use; Liposomes - chemistry; Male; Pain Management - methods; Pain, Postoperative - drug therapy; Particle Size; Sympathomimetics - administration & dosage; Sympathomimetics - therapeutic use

Lignocaine, first amino amide–type local anesthetic when combines or co-administered with Epinephrine, an sympathomimetic amine, allows larger doses for numbing, to decrease bleeding, and to make the numbing effect last longer. The present study focuses on measures to prove this activity in patients...