Optimized statistical parametric mapping for partial-volume-corrected amyloid positron emission tomography in patients with Alzheimer’s disease and Lewy body dementia

• Published in: Journal of the Korean Physical Society Vol. 70; no. 5; pp. 454 - 459
• Main Authors: Oh, Jungsu S., Kim, Jae Seung, Chae, Sun Young, Oh, Minyoung, Oh, Seung Jun, Cha, Seung Nam, Chang, Ho-Jong, Lee, Chong Sik, Lee, Jae Hong
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Physical Society 01.03.2017; Springer Nature B.V; 한국물리학회
• Subjects: Cerebrospinal fluid; Dementia; Image degradation; Magnetic resonance imaging; Mapping; Mathematical and Computational Physics; Medical imaging; Particle and Nuclear Physics; Physics; Physics and Astronomy; Positron emission; Signal to noise ratio; Smoothing; Theoretical; Tomography; Transfer matrices; 물리학; Partial volume correction; Alzheimer’s disease; Statistical parametric mapping; Positron emission tomography; Lewy body dementia

We present an optimized voxelwise statistical parametric mapping (SPM) of partial-volume (PV)-corrected positron emission tomography (PET) of 11 C Pittsburgh Compound B (PiB), incorporating the anatomical precision of magnetic resonance image (MRI) and amyloid β (A β ) burden-specificity of PiB PET....