Carnosol, a diterpene present in rosemary, increases ELP1 levels in familial Dysautonomia (FD) patient-derived cells and healthy adults: a possible therapy for FD

• Published in: Human molecular genetics Vol. 31; no. 20; pp. 3521 - 3538
• Main Authors: Anderson, Sylvia L, Fasih-Ahmad, Faaria, Evans, Anthony J, Rubin, Berish Y
• Format: Journal Article
• Language: English
• Published: England 10.10.2022

Recent research on Familial Dysautonomia (FD) has focused on the development of therapeutics that facilitate the production of the correctly spliced, exon 20-containing, transcript in cells and individuals bearing the splice-altering, FD-causing, mutation in the ELP1 gene. We report here the ability...