Comparison of methotrexate and azathioprine as the first-line steroid-sparing immunosuppressive agents in patients with Takayasu's arteritis

• Published in: Seminars in arthritis and rheumatism Vol. 66; p. 152446
• Main Authors: Kaymaz-Tahra, Sema, Bayindir, Ozun, Ince, Burak, Ozdemir İsik, Ozlem, Kutu, Muhammet Emin, Karakas, Ozlem, Yildirim, Tuba Demirci, Ademoglu, Zeliha, Ediboglu, Elif Durak, Uludogan, Burcu Ceren Ekti, Ilgin, Can, Bilge, Nazife Sule Yasar, Kasifoglu, Timucin, Akar, Servet, Emmungil, Hakan, Onen, Fatos, Omma, Ahmet, Kanitez, Nilufer Alpay, Yazici, Ayten, Cefle, Ayse, Inanc, Murat, Aksu, Kenan, Keser, Gokhan, Direskeneli, Haner, Alibaz-Oner, Fatma
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2024
• Subjects: Adult; Azathioprine; Azathioprine - therapeutic use; Female; Glucocorticoids - administration & dosage; Glucocorticoids - therapeutic use; Humans; Immunosuppressive; Immunosuppressive Agents - therapeutic use; Male; Methotrexate; Methotrexate - therapeutic use; Middle Aged; Retrospective Studies; Takayasu Arteritis - diagnostic imaging; Takayasu Arteritis - drug therapy; Takayasu's arteritis; Treatment Outcome; Immunosuppressive; Methotrexate; Azathioprine; Takayasu's arteritis

Immunosuppressive (IS) agents are recommended for the first-line treatment of patients with active Takayasu's arteritis (TAK) together with glucocorticoids (GCs). However, there is limited data comparing the efficacy and outcomes of different IS agents for this purpose. In this study, we aimed...