Normalization of plasma lipid peroxides, monocyte adhesion, and tumor necrosis factor-alpha production in NIDDM patients after gliclazide treatment

• Published in: Diabetes care Vol. 21; no. 4; pp. 487 - 493
• Main Authors: Desfaits, Anne-Cécile, Serri, Omar, Renier, Geneviève
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.04.1998
• Subjects: Animals; Aorta; Arteriosclerosis - prevention & control; Biological and medical sciences; Cattle; Cell Adhesion - drug effects; Cell Adhesion Molecules - blood; Cells, Cultured; Cytokines - blood; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - immunology; E-Selectin - blood; Endothelium, Vascular - physiology; Gliclazide - therapeutic use; Glyburide - therapeutic use; Hormones. Endocrine system; Humans; Hypoglycemic Agents - therapeutic use; Intercellular Adhesion Molecule-1 - blood; Interleukin-1 - blood; Interleukin-6 - biosynthesis; Interleukin-6 - blood; Lipid Peroxides - blood; Lipopolysaccharides - pharmacology; Medical sciences; Monocytes - drug effects; Monocytes - immunology; Monocytes - physiology; Pharmacology. Drug treatments; Reference Values; Treatment Failure; Tumor Necrosis Factor-alpha - biosynthesis; Vascular Cell Adhesion Molecule-1 - blood; Canada; North America; America; Endocrinopathy; Human; Monocyte; Treatment efficiency; Cytokine; Lipids; Adhesion; Non insulin dependent diabetes; Blood plasma; Endocrine secretion; Assay; Hypoglycemic agent; Chemotherapy; Treatment; Sulfonylureas; Gliclazide; Adult; Peroxides; Elderly; Comparative study

Normalization of plasma lipid peroxides, monocyte adhesion, and tumor necrosis factor-alpha production in NIDDM patients after gliclazide treatment. A C Desfaits , O Serri and G Renier Metabolic Unit, CHUM Research Center, Montreal, Quebec, Canada. Abstract OBJECTIVE: To evaluate the effect of glicl...