Metabolic dysfunction under reduced estrogen levels: looking to exercise for prevention

Loss of estrogen function leads to the development of metabolic dysfunction that spans numerous tissues. In this review, we explore the concept that estrogens are critical for defining metabolic function in adipose and hepatic tissues and also the possibility that exercise training should be conside...

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Bibliographic Details
Published inExercise and sport sciences reviews Vol. 40; no. 4; p. 195
Main Authors Spangenburg, Espen E, Wohlers, Lindsay M, Valencia, Ana P
Format Journal Article
LanguageEnglish
Published United States 01.10.2012
Subjects
Adipocytes - pathology
Adipose Tissue - metabolism
Animals
Estrogens - deficiency
Exercise
Female
Humans
Hypertrophy
Lipid Metabolism
Liver - metabolism
Physical Conditioning, Animal
Stearoyl-CoA Desaturase - metabolism
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Summary:Loss of estrogen function leads to the development of metabolic dysfunction that spans numerous tissues. In this review, we explore the concept that estrogens are critical for defining metabolic function in adipose and hepatic tissues and also the possibility that exercise training should be considered a substitute for estrogen replacement therapy in women with impairments in estrogen levels.
ISSN:1538-3008
DOI:10.1097/JES.0b013e31825eab9f