Cystatin C kidney functional reserve: a simple method to predict outcome in chronic kidney disease

• Published in: Nephrology, dialysis, transplantation Vol. 37; no. 6; pp. 1118 - 1124
• Main Authors: Christiadi, Daniel, Simpson, Charles, O’brien, Kate, Taylor, Kylie, Luxton, Grant, Rossleigh, Monica, Erlich, Jonathan, Endre, Zoltán H
• Format: Journal Article
• Language: English
• Published: England 25.05.2022
• Subjects: Adult; Biomarkers; Cohort Studies; Creatinine; Cystatin C; Glomerular Filtration Rate; Humans; Kidney - diagnostic imaging; Pentetic Acid; Renal Dialysis; Renal Insufficiency, Chronic; cystatin C; chronic kidney disease; renal reserve; KFR; major adverse kidney events; MAKE; kidney functional reserve

Kidney functional reserve (KFR), the only clinical kidney stress test, is not routinely measured because the complexity of measurement has limited clinical application. We investigated the utility of plasma cystatin C (CysC) after oral protein loading (PL) to determine KFR in Stages 3 and 4 chronic...