Silver‐Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes
Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver‐catalyzed dearomative [2π+2σ] cycloaddition strategy for the synthesis of indoline fused BCHs from N...
Saved in:
| Published in | Angewandte Chemie International Edition Vol. 62; no. 48 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
WEINHEIM
Wiley
27.11.2023
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver‐catalyzed dearomative [2π+2σ] cycloaddition strategy for the synthesis of indoline fused BCHs from N‐unprotected indoles and bicyclobutane precursors is described. The strain‐release dearomative cycloaddition operates under mild conditions, tolerating a wide range of functional groups. It is capable of forming BCHs with up to four contiguous quaternary carbon centers, achieving yields of up to 99 %. In addition, a scale‐up experiment and the synthetic transformations of the cycloadducts further highlighted the synthetic utility.
A silver Lewis acid catalyzes dearomative [2π+2σ] cycloadditions of N‐unprotected indoles and bicyclobutanes to afford indoline fused bicyclo[2.1.1]hexanes (BCHs) bearing up to four contiguous quaternary carbon centers in high yields and with an opposite regioselectivity compared to the classical pathway. |
|---|---|
| AbstractList | Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver‐catalyzed dearomative [2π+2σ] cycloaddition strategy for the synthesis of indoline fused BCHs from
N
‐unprotected indoles and bicyclobutane precursors is described. The strain‐release dearomative cycloaddition operates under mild conditions, tolerating a wide range of functional groups. It is capable of forming BCHs with up to four contiguous quaternary carbon centers, achieving yields of up to 99 %. In addition, a scale‐up experiment and the synthetic transformations of the cycloadducts further highlighted the synthetic utility. Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver-catalyzed dearomative [2 pi+2 sigma] cycloaddition strategy for the synthesis of indoline fused BCHs from N-unprotected indoles and bicyclobutane precursors is described. The strain-release dearomative cycloaddition operates under mild conditions, tolerating a wide range of functional groups. It is capable of forming BCHs with up to four contiguous quaternary carbon centers, achieving yields of up to 99 %. In addition, a scale-up experiment and the synthetic transformations of the cycloadducts further highlighted the synthetic utility. A silver Lewis acid catalyzes dearomative [2 pi+2 sigma] cycloadditions of N-unprotected indoles and bicyclobutanes to afford indoline fused bicyclo[2.1.1]hexanes (BCHs) bearing up to four contiguous quaternary carbon centers in high yields and with an opposite regioselectivity compared to the classical pathway.**+image Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space, but are difficult to access. Here a silver‐catalyzed dearomative [2π+2σ] cycloaddition strategy for the synthesis of indoline fused BCHs from N‐unprotected indoles and bicyclobutane precursors is described. The strain‐release dearomative cycloaddition operates under mild conditions, tolerating a wide range of functional groups. It is capable of forming BCHs with up to four contiguous quaternary carbon centers, achieving yields of up to 99 %. In addition, a scale‐up experiment and the synthetic transformations of the cycloadducts further highlighted the synthetic utility. A silver Lewis acid catalyzes dearomative [2π+2σ] cycloadditions of N‐unprotected indoles and bicyclobutanes to afford indoline fused bicyclo[2.1.1]hexanes (BCHs) bearing up to four contiguous quaternary carbon centers in high yields and with an opposite regioselectivity compared to the classical pathway. |
| Author | Xiao, Yuanjiu Feng, Jian‐Jun Wu, Feng Zhou, Jin‐Lan Tang, Lei Xu, Tong‐Tong |
| Author_xml | – sequence: 1 givenname: Lei orcidid: 0000-0003-1273-9040 surname: Tang fullname: Tang, Lei organization: Hunan University Changsha – sequence: 2 givenname: Yuanjiu orcidid: 0000-0001-5155-9099 surname: Xiao fullname: Xiao, Yuanjiu organization: Hunan University Changsha – sequence: 3 givenname: Feng orcidid: 0000-0003-1918-1596 surname: Wu fullname: Wu, Feng organization: Hunan University Changsha – sequence: 4 givenname: Jin‐Lan orcidid: 0000-0002-6313-4546 surname: Zhou fullname: Zhou, Jin‐Lan organization: Hunan University Changsha – sequence: 5 givenname: Tong‐Tong orcidid: 0000-0002-3979-1319 surname: Xu fullname: Xu, Tong‐Tong organization: Hunan University Changsha – sequence: 6 givenname: Jian‐Jun orcidid: 0000-0002-6094-3268 surname: Feng fullname: Feng, Jian‐Jun email: jianjunfeng@hnu.edu.cn organization: Hunan University Changsha |
| BookMark | eNqNkc1qFTEYhoNU7O_WdfZlxvxMJom747TVA0UX6qqUIcl8QyPTRCY5rcdVQXDtnfUeeiWd4RwqCKLZJIHneb-Qdx_thBgAoZeUlJQQ9soEDyUjjE-3un6G9qhgtOBS8p3pXHFeSCXoLtpP6cvEK0XqF2iXS8UYk3IP_fzohxsYH-5-NSabYf0dOnwCZozXJvsbwBfs_u6Y3f-4xM3aDdF0nc8-hoRjj5ehiwMkfOvzFX7j3QzYVTYB0mu8cA5SwjluMB8An63SlL4FL1hJS3p5Bd9m_hA9782Q4Gi7H6DPZ6efmnfF-Ye3y2ZxXjimdF1YKZh1Ne-V0LXWwmoNgtUUBDXcSCo6KyrNSG207CptnWOMy0opy6uOMMsP0PEm9xZs7JPzEBy0X0d_bcZ1SwglSlEmOZkWnWj1_3Tjs5m_pomrkCe13KhujCmN0D9plLRzc-3cXPvU3CRUfwhuG5hH44e_a3r7RD_A-h9D2sX75elv9xFe2a5d |
| CitedBy_id | crossref_primary_10_1002_ange_202420831 crossref_primary_10_1002_anie_202416741 crossref_primary_10_1002_ange_202418239 crossref_primary_10_1039_D4SC02998D crossref_primary_10_1039_D4QO02302A crossref_primary_10_1021_acscatal_5c00303 crossref_primary_10_1021_jacs_4c06436 crossref_primary_10_1039_D4QO01741B crossref_primary_10_1039_D4GC00703D crossref_primary_10_1002_anie_202402730 crossref_primary_10_1021_acs_orglett_4c01368 crossref_primary_10_1055_a_2406_3243 crossref_primary_10_1016_j_checat_2025_101295 crossref_primary_10_1021_jacsau_4c00839 crossref_primary_10_1055_a_2360_8218 crossref_primary_10_1016_j_chempr_2024_08_010 crossref_primary_10_1038_s41467_024_50434_6 crossref_primary_10_1039_D4SC06334A crossref_primary_10_1002_chem_202404099 crossref_primary_10_1039_D4GC03193H crossref_primary_10_1055_a_2367_2244 crossref_primary_10_1016_j_mcat_2024_114146 crossref_primary_10_1039_D4CC06133K crossref_primary_10_1039_D4QO02226B crossref_primary_10_1038_s41570_024_00623_0 crossref_primary_10_1002_ange_202402730 crossref_primary_10_1021_acs_orglett_4c01219 crossref_primary_10_1039_D4GC05355A crossref_primary_10_1021_acs_orglett_4c01775 crossref_primary_10_1021_acs_orglett_4c03798 crossref_primary_10_1039_D4SC03893B crossref_primary_10_1021_acscatal_5c00065 crossref_primary_10_1021_acs_orglett_4c01139 crossref_primary_10_1055_a_2456_9789 crossref_primary_10_1002_ange_202405781 crossref_primary_10_1021_acscatal_4c06660 crossref_primary_10_1016_j_tchem_2024_100070 crossref_primary_10_1021_jacs_4c10123 crossref_primary_10_1002_ange_202406548 crossref_primary_10_1021_jacs_4c11296 crossref_primary_10_1021_jacs_4c10968 crossref_primary_10_1038_s41467_024_48494_9 crossref_primary_10_1002_ajoc_202400599 crossref_primary_10_1002_ange_202416741 crossref_primary_10_1002_anie_202418239 crossref_primary_10_1021_jacs_4c01851 crossref_primary_10_1038_s44160_024_00659_6 crossref_primary_10_1002_anie_202420831 crossref_primary_10_1002_anie_202405781 crossref_primary_10_1021_jacs_4c04485 crossref_primary_10_1002_anie_202405222 crossref_primary_10_1002_anie_202407841 crossref_primary_10_1002_anie_202408578 crossref_primary_10_1021_acs_joc_4c01920 crossref_primary_10_1002_anie_202408610 crossref_primary_10_1038_s41467_024_52419_x crossref_primary_10_1021_jacs_4c04403 crossref_primary_10_1002_ajoc_202400045 crossref_primary_10_1002_ange_202405222 crossref_primary_10_1002_ange_202407841 crossref_primary_10_1002_anie_202406548 crossref_primary_10_1002_chem_202402965 crossref_primary_10_1021_acs_orglett_4c00421 crossref_primary_10_1002_ange_202408610 crossref_primary_10_1002_ange_202408578 crossref_primary_10_1021_acs_orglett_4c01512 crossref_primary_10_1021_jacs_4c10153 crossref_primary_10_1021_jacs_4c14276 crossref_primary_10_1039_D4QO00062E crossref_primary_10_1021_acscatal_4c05622 crossref_primary_10_1039_D4CC04730C crossref_primary_10_1039_D4SC07243J crossref_primary_10_1021_acs_orglett_4c04224 crossref_primary_10_1021_acscatal_4c05067 crossref_primary_10_1038_s41557_024_01710_x |
| Cites_doi | 10.1021/jacs.1c04180 10.1021/jacs.2c02976 10.1002/anie.202304246 10.1002/ajoc.201900589 10.1002/anie.202000548 10.1002/anie.202004183 10.1021/acs.orglett.6b02051 10.1021/acs.jmedchem.1c01215 10.1039/D2QO00167E 10.1021/ja403811t 10.1021/acs.orglett.5b01888 10.1002/anie.201914875 10.1039/C9CS00311H 10.1021/jm901241e 10.1021/acs.orglett.1c04071 10.1039/D0CC01771J 10.1002/anie.202304771 10.1038/s41586-022-05290-z 10.1039/D3SC03083K 10.1038/s41586-022-04636-x 10.1039/C8CS00389K 10.1002/cctc.202000743 10.1039/D0QO01124J 10.1002/anie.201904404 10.1038/s41467-022-33827-3 10.1021/acs.orglett.2c03606 10.1002/anie.201609608 10.1002/anie.202214507 10.1039/C8OB02812E 10.1016/j.cclet.2020.04.023 10.1021/jacs.1c10541 10.1038/s41557-023-01159-4 10.1021/jo015643r 10.1002/anie.202305043 10.1021/ja00955a021 10.1038/s42004-022-00811-3 10.1021/cr60302a003 10.1039/D2SC03948F 10.1021/ja067821 10.1021/jacs.2c13740 10.1038/s41557-023-01135-y 10.1038/s41586-020-2060-z 10.1038/s41586-023-06021-8 10.1021/acs.orglett.9b02026 10.1002/chem.201504894 10.1021/acs.jmedchem.8b00888 10.1021/jacs.1c03492 10.1021/acscatal.3c00305 10.1039/C5NP00076A 10.1038/s41557-023-01222-0 10.1002/cctc.201402940 10.1039/C4OB00371C 10.1021/jacs.2c13298 10.1021/jacs.2c05304 10.1126/science.adh9737 10.1021/ja01480a013 10.1016/j.chempr.2016.11.005 10.1039/C8RA03480J 10.1073/pnas.2108881118 10.1021/ar500167f 10.1126/science.aad6252 10.1038/s41467-022-34837-x 10.1021/jacs.3c02961 10.1021/jacs.3c02616 10.1016/S0040-4039(99)01107-7 10.1021/jacs.7b11865 10.1021/jacsau.3c00014 10.1002/anie.202205103 10.1021/ja00777a021 10.26434/chemrxiv-2023-s8j30 10.1016/j.chempr.2020.06.015 10.1021/acs.joc.7b02624 10.1021/acs.joc.7b03259 10.1021/acs.chemrev.6b00005 10.1002/anie.202204719 10.1039/D0QO00460J 10.1021/jacs.2c11501 10.1016/S0040-4020(01)87348-8 10.1055/s-0037-1610314 10.1021/jacs.2c09733 10.1021/jacs.0c00245 10.1039/c2md20347b 10.1039/C6CS00107F 10.1002/anie.201006017 10.1021/ja4042127 10.1002/anie.201908951 10.1021/jacs.2c09045 10.1002/anie.202011739 10.1002/anie.200600723 10.1021/acscatal.6b03399 10.1021/ja802906k 10.1002/anie.202106352 10.1039/D3SC03258B 10.1039/D3SC01373A 10.1021/jacs.2c09248 10.1021/ar500437h 10.1021/acs.accounts.9b00623 10.1021/acscentsci.0c01651 10.1038/s41557-021-00786-z 10.1039/D1SC00161B 10.1038/s41557-018-0181-x 10.1039/D1SC01127H 10.1515/pac-2019-1007 10.1039/d1sc01127h 10.1039/c5np00076a 10.1039/c8ob02812e 10.1039/d3sc01373a 10.1002/anie.202309030 10.1039/d3sc03258b 10.1039/d2qo00167e 10.1039/c8ra03480j 10.1039/d1sc00161b 10.1039/d0cc01771j 10.1039/d3sc03083k 10.1039/c8cs00389k 10.1039/d0qo01124j 10.1039/d0qo00460j 10.1039/c4ob00371c 10.1039/c6cs00107f 10.1021/ja067821+ 10.1039/c9cs00311h 10.1039/d2sc03948f |
| ContentType | Journal Article |
| Copyright | 2023 Wiley‐VCH GmbH |
| Copyright_xml | – notice: 2023 Wiley‐VCH GmbH |
| DBID | AAYXX CITATION 17B 1KM 1KN BLEPL BNZSX DTL EGQ |
| DOI | 10.1002/anie.202310066 |
| DatabaseName | CrossRef Web of Knowledge Index Chemicus Current Chemical Reactions Web of Science Core Collection Web of Science - Science Citation Index Expanded - 2023 Science Citation Index Expanded Web of Science Primary (SCIE, SSCI & AHCI) |
| DatabaseTitle | CrossRef Web of Science |
| DatabaseTitleList | CrossRef Web of Science |
| Database_xml | – sequence: 1 dbid: 1KN name: Current Chemical Reactions url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/woscc/search-with-editions?editions=WOS.CCR sourceTypes: Enrichment Source Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Chemistry |
| EISSN | 1521-3773 |
| EndPage | n/a |
| ExternalDocumentID | 001088127300001 10_1002_anie_202310066 ANIE202310066 |
| Genre | shortCommunication |
| GrantInformation_xml | – fundername: the Fundamental Research Funds for the Central Universities – fundername: We are grateful to the Fundamental Research Funds for the Central Universities for financial support. We also thank Prof. Dr. Junliang Zhang (Fudan University) for helpful discussions. The 1H, 13C NMR spectra and HRMS (ESI) were perfo – fundername: Fundamental Research Funds for the Central Universities |
| GroupedDBID | --- -DZ -~X .3N .GA 05W 0R~ 10A 1L6 1OB 1OC 1ZS 23M 33P 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5RE 5VS 66C 6TJ 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHQN AAMNL AANLZ AAONW AAXRX AAYCA AAZKR ABCQN ABCUV ABDBF ABEML ABIJN ABJNI ABLJU ABPPZ ABPVW ACAHQ ACCZN ACFBH ACGFS ACIWK ACNCT ACPOU ACPRK ACSCC ACXBN ACXQS ADBBV ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN AEIGN AEIMD AEUYR AEYWJ AFBPY AFFNX AFFPM AFGKR AFRAH AFWVQ AFZJQ AGHNM AGYGG AHBTC AHMBA AITYG AIURR AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB ATUGU AUFTA AZBYB AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BTSUX BY8 CS3 D-E D-F D0L DCZOG DPXWK DR1 DR2 DRFUL DRSTM EBS F00 F01 F04 F5P G-S G.N GNP GODZA H.T H.X HBH HGLYW HHY HHZ HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LYRES M53 MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- OIG P2P P2W P2X P4D PQQKQ Q.N Q11 QB0 QRW R.K RNS ROL RX1 RYL SUPJJ TN5 UB1 UPT UQL V2E W8V W99 WBFHL WBKPD WH7 WIB WIH WIK WJL WOHZO WQJ WXSBR WYISQ XG1 XPP XSW XV2 YZZ ZZTAW ~IA ~KM ~WT AAHHS AAYXX ACCFJ ADZOD AEEZP AEQDE AIWBW AJBDE CITATION 17B 1KM 1KN BLEPL DTL GROUPED_WOS_SCIENCE_CITATION_INDEX_EXPANDED GROUPED_WOS_WEB_OF_SCIENCE |
| ID | FETCH-LOGICAL-c2896-b752bc63f8596995b99e5261e51a3a715db549206a97d49bcc2237488b34d02b3 |
| IEDL.DBID | DR2 |
| ISICitedReferencesCount | 94 |
| ISICitedReferencesURI | https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=CitingArticles&UT=001088127300001 |
| ISSN | 1433-7851 |
| IngestDate | Wed Jul 09 18:02:32 EDT 2025 Fri Aug 29 16:15:22 EDT 2025 Tue Jul 01 01:47:22 EDT 2025 Thu Apr 24 23:08:34 EDT 2025 Sun Jul 06 04:45:54 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 48 |
| Keywords | Heterocycles ASYMMETRIC DEAROMATIZATION CYCLOPENTANNULATION STRAIN-RELEASE ANNULATION REARRANGEMENTS STRATEGIES Cycloaddition 3-ALKYLINDOLES Bioisosteres Strained Molecules CONSTRUCTION COMPLEXITY CHEMISTRY Bicyclic Compounds |
| Language | English |
| LinkModel | DirectLink |
| LogoURL | https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg |
| MergedId | FETCHMERGED-LOGICAL-c2896-b752bc63f8596995b99e5261e51a3a715db549206a97d49bcc2237488b34d02b3 |
| Notes | These authors contributed equally to this work. https://doi.org/10.26434/chemrxiv‐2023‐qkzmk . A previous version of this manuscript has been deposited on a preprint server |
| ORCID | 0000-0001-5155-9099 0000-0002-6313-4546 0000-0002-6094-3268 0000-0002-3979-1319 0000-0003-1918-1596 0000-0003-1273-9040 |
| PMID | 37822277 |
| PageCount | 6 |
| ParticipantIDs | webofscience_primary_001088127300001 wiley_primary_10_1002_anie_202310066_ANIE202310066 crossref_primary_10_1002_anie_202310066 crossref_citationtrail_10_1002_anie_202310066 webofscience_primary_001088127300001CitationCount |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | November 27, 2023 2023-11-27 |
| PublicationDateYYYYMMDD | 2023-11-27 |
| PublicationDate_xml | – month: 11 year: 2023 text: November 27, 2023 day: 27 |
| PublicationDecade | 2020 |
| PublicationPlace | WEINHEIM |
| PublicationPlace_xml | – name: WEINHEIM |
| PublicationTitle | Angewandte Chemie International Edition |
| PublicationTitleAbbrev | ANGEW CHEM INT EDIT |
| PublicationYear | 2023 |
| Publisher | Wiley |
| Publisher_xml | – name: Wiley |
| References | 2017; 7 2013; 4 2021; 64 2017; 82 2023; 6 2019; 11 2023; 381 2023; 145 2019; 58 2019; 17 2022; 24 2020; 59 2020; 56 2020; 12 2018; 83 1999; 40 2023; 3 2022; 611 2018; 47 1976; 76 2020; 7 2023; 62 2020; 6 2015; 48 2018; 8 2009; 52 2019; 62 2020; 53 1986; 42 2019; 21 2020; 92 2020; 9 2021; 118 2017; 34 1972; 94 1961; 83 2016; 116 2022; 605 2023; 618 2014; 12 2016; 351 2016; 45 2021; 7 2015; 17 2023; 13 2007; 129 2023; 14 2019; 30 2020; 580 2023; 15 2020; 142 2022; 51 2014; 47 2021; 143 2001; 66 2016; 18 2015; 7 2017; 139 2022; 144 2021; 13 2016; 1 2021; 12 2020; 31 2023 2006; 45 2022; 61 2022; 9 2011; 50 2017; 56 2022; 13 2013; 135 2021; 60 1966; 88 2008; 130 2016; 22 e_1_2_3_73_1 e_1_2_3_50_2 e_1_2_3_92_2 e_1_2_3_114_2 e_1_2_3_110_2 e_1_2_3_4_2 e_1_2_3_16_2 e_1_2_3_39_2 e_1_2_3_8_2 e_1_2_3_12_2 e_1_2_3_58_2 e_1_2_3_77_2 e_1_2_3_35_2 e_1_2_3_54_2 e_1_2_3_96_2 e_1_2_3_31_2 e_1_2_3_118_1 e_1_2_3_62_1 e_1_2_3_81_2 e_1_2_3_102_1 e_1_2_3_28_2 e_1_2_3_24_2 e_1_2_3_47_2 e_1_2_3_66_2 e_1_2_3_89_1 e_1_2_3_106_2 e_1_2_3_20_2 e_1_2_3_43_2 e_1_2_3_85_2 e_1_2_3_72_2 e_1_2_3_91_2 e_1_2_3_19_2 e_1_2_3_115_2 e_1_2_3_15_2 e_1_2_3_38_2 e_1_2_3_111_2 e_1_2_3_3_2 e_1_2_3_11_2 e_1_2_3_34_2 e_1_2_3_7_2 e_1_2_3_57_2 e_1_2_3_99_2 e_1_2_3_119_1 e_1_2_3_30_2 e_1_2_3_76_2 e_1_2_3_53_2 e_1_2_3_95_2 e_1_2_3_84_1 e_1_2_3_61_2 e_1_2_3_80_2 e_1_2_3_103_2 e_1_2_3_27_2 e_1_2_3_23_2 e_1_2_3_69_2 e_1_2_3_46_2 e_1_2_3_88_2 e_1_2_3_65_2 e_1_2_3_42_2 e_1_2_3_107_2 e_1_2_3_71_2 e_1_2_3_94_2 e_1_2_3_90_1 e_1_2_3_112_2 e_1_2_3_37_2 e_1_2_3_2_2 e_1_2_3_18_2 e_1_2_3_56_2 e_1_2_3_79_2 e_1_2_3_33_2 e_1_2_3_14_1 e_1_2_3_6_2 e_1_2_3_75_2 e_1_2_3_52_1 e_1_2_3_98_1 e_1_2_3_116_2 e_1_2_3_10_2 e_1_2_3_60_2 e_1_2_3_83_2 e_1_2_3_104_2 e_1_2_3_26_2 e_1_2_3_49_2 e_1_2_3_100_2 e_1_2_3_22_2 e_1_2_3_68_2 e_1_2_3_45_1 e_1_2_3_41_2 e_1_2_3_64_2 e_1_2_3_87_2 e_1_2_3_108_1 e_1_2_3_93_2 e_1_2_3_70_2 e_1_2_3_1_1 e_1_2_3_113_2 e_1_2_3_5_1 e_1_2_3_17_2 e_1_2_3_59_2 e_1_2_3_9_2 e_1_2_3_13_2 e_1_2_3_36_2 e_1_2_3_78_2 e_1_2_3_51_2 e_1_2_3_97_2 e_1_2_3_55_1 e_1_2_3_117_1 e_1_2_3_32_1 e_1_2_3_74_2 e_1_2_3_82_2 e_1_2_3_101_2 e_1_2_3_48_2 e_1_2_3_120_1 e_1_2_3_29_2 e_1_2_3_44_2 e_1_2_3_109_2 e_1_2_3_25_1 e_1_2_3_67_2 e_1_2_3_40_2 e_1_2_3_86_2 e_1_2_3_105_2 e_1_2_3_21_2 e_1_2_3_63_2 Huang, WC (WOS:000828488000001) 2022; 144 Dibchak, D (WOS:001007996600001) 2023; 62 Fawcett, A (WOS:000456665900007) 2019; 11 Zheng, YX (WOS:000903236700001) 2022; 144 Panish, R (WOS:000321236600013) 2013; 135 Lovering, F (WOS:000271427900027) 2009; 52 Liu, Y (WOS:000971587200001) 2023; 13 Pirenne, V (WOS:000654359200001) 2021; 12 Rigotti, T (WOS:000890722600001) 2022 Guo, L (WOS:000585833800001) 2021; 60 Sun, M (WOS:000427094200067) 2018; 83 Turkowska, J (WOS:000537959100028) 2020; 56 Zheng, C (WOS:000634764100009) 2021; 7 Dhake, K (WOS:000790027100001) 2022; 61 Wertjes, WC (WOS:000448662800009) 2018; 47 Anderson, JM (WOS:000682494400001) 2021; 60 Walczak, MAA (WOS:000353429400026) 2015; 48 Subbaiah, MAM (WOS:000709633100007) 2021; 64 Golfmann, M (WOS:000913525100001) 2023; 6 Wang, HM (WOS:001030999200030) 2023; 381 Chen, PP (WOS:000888871600011) 2022; 13 Robertson, J (WOS:000392479800003) 2017; 34 Zheng, QZ (WOS:000381438600010) 2016; 45 WIBERG, KB (WOS:A19613058B00044) 1961; 83 Milligan, JA (WOS:000382711200039) 2016; 18 Schwartz, BD (WOS:000743540500001) 2022; 24 Liang, YJ (WOS:000887076900001) 2022; 144 Feng, JJ (WOS:000395726500003) 2017; 7 Mykhailiuk, PK (WOS:000461223700026) 2019; 17 Walczak, MAA (WOS:000256301200016) 2008; 130 Cheng, YZ (WOS:000760929500001) 2022; 51 Guin, A (WOS:001012087800001) 2023; 14 Zhang, XH (WOS:000522805100001) 2020; 580 Zhuo, CX (WOS:000340702000032) 2014; 47 Pinkert, T (WOS:000657212800010) 2021; 143 Gianatassio, R (WOS:000368098600032) 2016; 351 Zhu, PL (WOS:000349917900008) 2015; 7 DEMEIJERE, A (WOS:A1986A540600007) 1986; 42 Agasti, S (WOS:000933339300001) 2023; 15 Epplin, RC (WOS:000868657300014) 2022; 13 Shire, BR (WOS:001012251300001) 2023; 3 Reekie, TA (WOS:000459223600002) 2019; 62 Liang, Y (WOS:001041551200001) 2023; 62 Kleinnijenhuis, RA (WOS:000368922500012) 2016; 22 CAIRNCROSS, A (WOS:A19667263600021) 1966; 88 Radhoff, N (WOS:001008962500001) 2023; 62 Zhu, CZ (WOS:000394997700031) 2017; 56 PAQUETTE, LA (WOS:A1972N906500026) 1972; 94 Lovering, F (WOS:000315355800005) 2013; 4 Sheng, FT (WOS:000592311700013) 2020; 7 Gee, YS (WOS:000418392600055) 2017; 82 Xu, M (WOS:000890467600001) 2022; 61 Bychek, R (WOS:000810708000001) 2022; 61 Kanazawa, J (WOS:000418204600023) 2017; 139 Denisenko, A (WOS:001000894300001) 2023; 15 Takao, K (WOS:000476615900024) 2019; 58 Ociepa, M (WOS:000526392600047) 2020; 142 Nguyen, T. V. T. (001088127300001.44) 2023 Huck, CJ (WOS:000558678900014) 2020; 6 Wang, M (WOS:000766792000001) 2022; 9 Zhao, JX (WOS:000685035200004) 2021; 118 Wright, BA (WOS:000983351000001) 2023; 145 Ernouf, G (WOS:000494501000001) 2020; 59 Ma, XS (WOS:000501671600001) 2020; 9 Remy, R (WOS:000383410100006) 2016; 116 England, DB (WOS:000169536700034) 2001; 66 Kerr, MA (WOS:000081543000007) 1999; 40 Tang, L (WOS:001064597400001) 2023; 14 Li, M (WOS:000567416500001) 2020; 12 Saya, JM (WOS:000359393800064) 2015; 17 Xiong, H (WOS:000319856700016) 2013; 135 Ding, QP (WOS:000338118400002) 2014; 12 BISHOP, KC (WOS:A1976BY80200003) 1976; 76 Ma, XS (WOS:000487577200003) 2019; 21 Kleinmans, R (WOS:000793701100001) 2022; 605 He, FS (WOS:000600917100012) 2020; 31 Yu, SJ (WOS:000509718000001) 2020; 59 Fawcett, A (WOS:000537416000006) 2020; 92 Iida, T (WOS:000883756300001) 2022; 144 Reinhold, M (WOS:001058076900001) 2023; 14 Wipf, P (WOS:000238718500022) 2006; 45 Caplin, MJ (WOS:000637925000001) 2021; 12 Kelly, CB (WOS:000848123300001) 2022; 13 Bajtos, B (WOS:000248484400044) 2007; 129 Yu, IF (WOS:000959282800003) 2023; 15 Yu, T. (001088127300001.45) 2023; 145 Levterov, VV (WOS:000520307500001) 2020; 59 Pramanik, MMD (WOS:000562454200020) 2020; 7 Pickford, HD (WOS:000672592000004) 2021; 143 Kanazawa, J (WOS:000453250700001) 2019; 30 Harmata, AS (WOS:000731578000001) 2021; 143 Roche, SP (WOS:000290662500006) 2011; 50 Zheng, C (WOS:000389801600008) 2016; 1 Zhang, ZY (WOS:000879942700001) 2022; 144 Guo, RY (WOS:000799180800007) 2022; 144 Huang, WC (WOS:000935916900001) 2023 Kleinmans, R (WOS:001005914100001) 2023; 145 Wiesenfeldt, MP (WOS:001003548000001) 2023; 618 Vivekanand, T (WOS:000433428300048) 2018; 8 Sivaguru, P (WOS:000526398000012) 2020; 53 Denisenko, A (WOS:000560930500001) 2020; 59 Yang, YY (WOS:000701641300003) 2021; 13 Frank, N (WOS:000869346300001) 2022; 611 |
| References_xml | – volume: 52 start-page: 6752 year: 2009 end-page: 6756 publication-title: J. Med. Chem. – volume: 7 start-page: 1533 year: 2017 end-page: 1542 publication-title: ACS Catal. – volume: 40 start-page: 5671 year: 1999 end-page: 5675 publication-title: Tetrahedron Lett. – volume: 22 start-page: 1266 year: 2016 end-page: 1269 publication-title: Chem. Eur. J. – volume: 13 start-page: 6056 year: 2022 publication-title: Nat. Commun. – volume: 143 start-page: 7648 year: 2021 end-page: 7654 publication-title: J. Am. Chem. Soc. – volume: 56 start-page: 1351 year: 2017 end-page: 1355 publication-title: Angew. Chem. Int. Ed. – volume: 145 start-page: 5363 year: 2023 end-page: 5369 publication-title: J. Am. Chem. Soc. – volume: 12 start-page: 5034 year: 2020 end-page: 5050 publication-title: ChemCatChem – volume: 88 start-page: 496 year: 1966 end-page: 504 publication-title: J. Am. Chem. Soc. – volume: 59 start-page: 3917 year: 2020 end-page: 3921 publication-title: Angew. Chem. Int. Ed. – volume: 14 start-page: 9696 year: 2023 end-page: 9703 publication-title: Chem. Sci. – volume: 15 start-page: 535 year: 2023 end-page: 541 publication-title: Nat. Chem. – volume: 17 start-page: 3892 year: 2015 end-page: 3894 publication-title: Org. Lett. – volume: 45 start-page: 4172 year: 2006 end-page: 4175 publication-title: Angew. Chem. Int. Ed. – volume: 42 start-page: 1291 year: 1986 end-page: 1297 publication-title: Tetrahedron – volume: 144 start-page: 21848 year: 2022 end-page: 21852 publication-title: J. Am. Chem. Soc. – volume: 13 start-page: 5096 year: 2023 end-page: 5103 publication-title: ACS Catal. – volume: 605 start-page: 477 year: 2022 end-page: 482 publication-title: Nature – volume: 145 start-page: 10960 year: 2023 end-page: 10966 publication-title: J. Am. Chem. Soc. – volume: 6 start-page: 9 year: 2023 publication-title: Commun. Chem. – volume: 47 start-page: 2558 year: 2014 end-page: 2573 publication-title: Acc. Chem. Res. – volume: 48 start-page: 1149 year: 2015 end-page: 1158 publication-title: Acc. Chem. Res. – volume: 145 start-page: 12324 year: 2023 end-page: 12332 publication-title: J. Am. Chem. Soc. – volume: 62 start-page: 1078 year: 2019 end-page: 1095 publication-title: J. Med. Chem. – volume: 21 start-page: 7199 year: 2019 end-page: 7203 publication-title: Org. Lett. – volume: 34 start-page: 62 year: 2017 end-page: 89 publication-title: Nat. Prod. Rep. – volume: 17 start-page: 2839 year: 2019 end-page: 2849 publication-title: Org. Biomol. Chem. – volume: 83 start-page: 2341 year: 2018 end-page: 2348 publication-title: J. Org. Chem. – volume: 47 start-page: 7996 year: 2018 end-page: 8017 publication-title: Chem. Soc. Rev. – volume: 145 start-page: 4304 year: 2023 end-page: 4310 publication-title: J. Am. Chem. Soc. – volume: 351 start-page: 241 year: 2016 end-page: 246 publication-title: Science – volume: 7 start-page: 432 year: 2021 end-page: 444 publication-title: ACS Cent. Sci. – volume: 1 start-page: 830 year: 2016 end-page: 857 publication-title: Chem – volume: 3 start-page: 1539 year: 2023 end-page: 1553 publication-title: JACS Au – volume: 6 start-page: 1589 year: 2020 end-page: 1603 publication-title: Chem – volume: 142 start-page: 5355 year: 2020 end-page: 5361 publication-title: J. Am. Chem. Soc. – volume: 59 start-page: 20515 year: 2020 end-page: 20521 publication-title: Angew. Chem. Int. Ed. – volume: 618 start-page: 513 year: 2023 end-page: 518 publication-title: Nature – year: 2023 publication-title: Chem. Sci. – volume: 143 start-page: 21223 year: 2021 end-page: 21228 publication-title: J. Am. Chem. Soc. – volume: 24 start-page: 8821 year: 2022 end-page: 8825 publication-title: Org. Lett. – volume: 130 start-page: 6924 year: 2008 end-page: 6925 publication-title: J. Am. Chem. Soc. – volume: 8 start-page: 18576 year: 2018 end-page: 18588 publication-title: RSC Adv. – volume: 15 start-page: 1155 year: 2023 end-page: 1163 publication-title: Nat. Chem. – year: 2023 publication-title: ChemRxiv preprint – volume: 60 start-page: 212 year: 2021 end-page: 216 publication-title: Angew. Chem. Int. Ed. – volume: 144 start-page: 7988 year: 2022 end-page: 7994 publication-title: J. Am. Chem. Soc. – volume: 53 start-page: 662 year: 2020 end-page: 675 publication-title: Acc. Chem. Res. – volume: 144 start-page: 20207 year: 2022 end-page: 20213 publication-title: J. Am. Chem. Soc. – volume: 144 start-page: 12961 year: 2022 end-page: 12969 publication-title: J. Am. Chem. Soc. – volume: 18 start-page: 4300 year: 2016 end-page: 4303 publication-title: Org. Lett. – volume: 135 start-page: 7851 year: 2013 end-page: 7854 publication-title: J. Am. Chem. Soc. – volume: 94 start-page: 7780 year: 1972 end-page: 7788 publication-title: J. Am. Chem. Soc. – volume: 12 start-page: 4807 year: 2014 end-page: 4815 publication-title: Org. Biomol. Chem. – volume: 7 start-page: 2531 year: 2020 end-page: 2537 publication-title: Org. Chem. Front. – volume: 12 start-page: 8706 year: 2021 end-page: 8712 publication-title: Chem. Sci. – volume: 51 start-page: 2145 year: 2022 end-page: 2170 publication-title: Chem. Soc. Rev. – volume: 12 start-page: 4646 year: 2021 end-page: 4660 publication-title: Chem. Sci. – volume: 82 start-page: 13517 year: 2017 end-page: 13529 publication-title: J. Org. Chem. – volume: 76 start-page: 461 year: 1976 end-page: 486 publication-title: Chem. Rev. – volume: 24 start-page: 1268 year: 2022 end-page: 1273 publication-title: Org. Lett. – volume: 13 start-page: 7292 year: 2022 publication-title: Nat. Commun. – volume: 66 start-page: 4704 year: 2001 end-page: 4709 publication-title: J. Org. Chem. – volume: 50 start-page: 4068 year: 2011 end-page: 4093 publication-title: Angew. Chem. Int. Ed. – volume: 64 start-page: 14046 year: 2021 end-page: 14128 publication-title: J. Med. Chem. – volume: 129 start-page: 9631 year: 2007 end-page: 9634 publication-title: J. Am. Chem. Soc. – volume: 56 start-page: 5718 year: 2020 end-page: 5734 publication-title: Chem. Commun. – volume: 62 year: 2023 publication-title: Angew. Chem. Int. Ed. – volume: 9 start-page: 2149 year: 2022 end-page: 2153 publication-title: Org. Chem. Front. – volume: 45 start-page: 4590 year: 2016 end-page: 4627 publication-title: Chem. Soc. Rev. – volume: 135 start-page: 9283 year: 2013 end-page: 9286 publication-title: J. Am. Chem. Soc. – volume: 31 start-page: 3065 year: 2020 end-page: 3072 publication-title: Chin. Chem. Lett. – volume: 30 start-page: 1 year: 2019 end-page: 11 publication-title: Synlett – volume: 59 start-page: 7161 year: 2020 end-page: 7167 publication-title: Angew. Chem. Int. Ed. – volume: 580 start-page: 220 year: 2020 end-page: 226 publication-title: Nature – volume: 4 start-page: 515 year: 2013 end-page: 519 publication-title: MedChemComm – volume: 61 year: 2022 publication-title: Angew. Chem. Int. Ed. – volume: 144 start-page: 20875 year: 2022 end-page: 20883 publication-title: J. Am. Chem. Soc. – volume: 83 start-page: 3998 year: 1961 end-page: 4006 publication-title: J. Am. Chem. Soc. – volume: 11 start-page: 117 year: 2019 end-page: 122 publication-title: Nat. Chem. – volume: 7 start-page: 595 year: 2015 end-page: 600 publication-title: ChemCatChem – volume: 15 start-page: 685 year: 2023 end-page: 693 publication-title: Nat. Chem. – volume: 14 start-page: 6585 year: 2023 end-page: 6591 publication-title: Chem. Sci. – volume: 116 start-page: 9816 year: 2016 end-page: 9849 publication-title: Chem. Rev. – volume: 92 start-page: 751 year: 2020 end-page: 765 publication-title: Pure Appl. Chem. – volume: 58 start-page: 9851 year: 2019 end-page: 9855 publication-title: Angew. Chem. Int. Ed. – volume: 9 start-page: 8 year: 2020 end-page: 22 publication-title: Asian J. Org. Chem. – volume: 144 start-page: 23685 year: 2022 end-page: 23690 publication-title: J. Am. Chem. Soc. – volume: 13 start-page: 11721 year: 2022 end-page: 11737 publication-title: Chem. Sci. – volume: 611 start-page: 721 year: 2022 end-page: 726 publication-title: Nature – volume: 139 start-page: 17791 year: 2017 end-page: 17794 publication-title: J. Am. Chem. Soc. – volume: 118 year: 2021 publication-title: Proc. Natl. Acad. Sci. USA – volume: 59 start-page: 2618 year: 2020 end-page: 2622 publication-title: Angew. Chem. Int. Ed. – volume: 13 start-page: 950 year: 2021 end-page: 955 publication-title: Nat. Chem. – volume: 7 start-page: 3967 year: 2020 end-page: 3998 publication-title: Org. Chem. Front. – volume: 60 start-page: 24754 year: 2021 end-page: 24769 publication-title: Angew. Chem. Int. Ed. – volume: 143 start-page: 9729 year: 2021 end-page: 9736 publication-title: J. Am. Chem. Soc. – volume: 381 start-page: 75 year: 2023 end-page: 81 publication-title: Science – ident: e_1_2_3_43_2 doi: 10.1021/jacs.1c04180 – ident: e_1_2_3_78_2 doi: 10.1021/jacs.2c02976 – ident: e_1_2_3_13_2 doi: 10.1002/anie.202304246 – ident: e_1_2_3_29_2 doi: 10.1002/ajoc.201900589 – ident: e_1_2_3_11_2 doi: 10.1002/anie.202000548 – ident: e_1_2_3_53_2 doi: 10.1002/anie.202004183 – ident: e_1_2_3_110_2 doi: 10.1021/acs.orglett.6b02051 – ident: e_1_2_3_6_2 doi: 10.1021/acs.jmedchem.1c01215 – ident: e_1_2_3_87_2 doi: 10.1039/D2QO00167E – ident: e_1_2_3_109_2 doi: 10.1021/ja403811t – ident: e_1_2_3_73_1 – ident: e_1_2_3_108_1 – ident: e_1_2_3_57_2 doi: 10.1021/acs.orglett.5b01888 – ident: e_1_2_3_35_2 doi: 10.1002/anie.201914875 – ident: e_1_2_3_15_2 doi: 10.1039/C9CS00311H – ident: e_1_2_3_2_2 doi: 10.1021/jm901241e – ident: e_1_2_3_83_2 doi: 10.1021/acs.orglett.1c04071 – ident: e_1_2_3_66_2 doi: 10.1039/D0CC01771J – ident: e_1_2_3_81_2 doi: 10.1002/anie.202304771 – ident: e_1_2_3_47_2 doi: 10.1038/s41586-022-05290-z – ident: e_1_2_3_61_2 doi: 10.1039/D3SC03083K – ident: e_1_2_3_77_2 doi: 10.1038/s41586-022-04636-x – ident: e_1_2_3_19_2 doi: 10.1039/C8CS00389K – ident: e_1_2_3_106_2 doi: 10.1002/cctc.202000743 – ident: e_1_2_3_18_2 doi: 10.1039/D0QO01124J – ident: e_1_2_3_59_2 doi: 10.1002/anie.201904404 – ident: e_1_2_3_10_2 doi: 10.1038/s41467-022-33827-3 – ident: e_1_2_3_60_2 doi: 10.1021/acs.orglett.2c03606 – ident: e_1_2_3_99_2 doi: 10.1002/anie.201609608 – ident: e_1_2_3_79_2 doi: 10.1002/anie.202214507 – ident: e_1_2_3_7_2 doi: 10.1039/C8OB02812E – ident: e_1_2_3_30_2 doi: 10.1016/j.cclet.2020.04.023 – ident: e_1_2_3_46_2 doi: 10.1021/jacs.1c10541 – ident: e_1_2_3_62_1 – ident: e_1_2_3_44_2 doi: 10.1038/s41557-023-01159-4 – ident: e_1_2_3_95_2 doi: 10.1021/jo015643r – ident: e_1_2_3_88_2 doi: 10.1002/anie.202305043 – ident: e_1_2_3_120_1 – ident: e_1_2_3_84_1 – ident: e_1_2_3_74_2 doi: 10.1021/ja00955a021 – ident: e_1_2_3_63_2 doi: 10.1038/s42004-022-00811-3 – ident: e_1_2_3_104_2 doi: 10.1021/cr60302a003 – ident: e_1_2_3_45_1 – ident: e_1_2_3_64_2 doi: 10.1039/D2SC03948F – ident: e_1_2_3_92_2 doi: 10.1021/ja067821 – ident: e_1_2_3_14_1 – ident: e_1_2_3_51_2 doi: 10.1021/jacs.2c13740 – ident: e_1_2_3_54_2 doi: 10.1038/s41557-023-01135-y – ident: e_1_2_3_52_1 – ident: e_1_2_3_36_2 doi: 10.1038/s41586-020-2060-z – ident: e_1_2_3_55_1 – ident: e_1_2_3_9_2 doi: 10.1038/s41586-023-06021-8 – ident: e_1_2_3_71_2 doi: 10.1021/acs.orglett.9b02026 – ident: e_1_2_3_117_1 – ident: e_1_2_3_58_2 doi: 10.1002/chem.201504894 – ident: e_1_2_3_90_1 – ident: e_1_2_3_8_2 doi: 10.1021/acs.jmedchem.8b00888 – ident: e_1_2_3_70_2 doi: 10.1021/jacs.1c03492 – ident: e_1_2_3_80_2 doi: 10.1021/acscatal.3c00305 – ident: e_1_2_3_118_1 doi: 10.1039/C5NP00076A – ident: e_1_2_3_12_2 doi: 10.1038/s41557-023-01222-0 – ident: e_1_2_3_119_1 doi: 10.1002/cctc.201402940 – ident: e_1_2_3_23_2 doi: 10.1039/C4OB00371C – ident: e_1_2_3_41_2 doi: 10.1021/jacs.2c13298 – ident: e_1_2_3_40_2 doi: 10.1021/jacs.2c05304 – ident: e_1_2_3_72_2 doi: 10.1126/science.adh9737 – ident: e_1_2_3_56_2 doi: 10.1021/ja01480a013 – ident: e_1_2_3_20_2 doi: 10.1016/j.chempr.2016.11.005 – ident: e_1_2_3_5_1 – ident: e_1_2_3_89_1 doi: 10.1039/C8RA03480J – ident: e_1_2_3_37_2 doi: 10.1073/pnas.2108881118 – ident: e_1_2_3_22_2 doi: 10.1021/ar500167f – ident: e_1_2_3_33_2 doi: 10.1126/science.aad6252 – ident: e_1_2_3_69_2 doi: 10.1038/s41467-022-34837-x – ident: e_1_2_3_82_2 doi: 10.1021/jacs.3c02961 – ident: e_1_2_3_42_2 doi: 10.1021/jacs.3c02616 – ident: e_1_2_3_102_1 – ident: e_1_2_3_96_2 doi: 10.1016/S0040-4039(99)01107-7 – ident: e_1_2_3_34_2 doi: 10.1021/jacs.7b11865 – ident: e_1_2_3_26_2 doi: 10.1021/jacsau.3c00014 – ident: e_1_2_3_32_1 – ident: e_1_2_3_39_2 doi: 10.1002/anie.202205103 – ident: e_1_2_3_103_2 doi: 10.1021/ja00777a021 – ident: e_1_2_3_50_2 doi: 10.26434/chemrxiv-2023-s8j30 – ident: e_1_2_3_1_1 – ident: e_1_2_3_17_2 doi: 10.1016/j.chempr.2020.06.015 – ident: e_1_2_3_93_2 doi: 10.1021/acs.joc.7b02624 – ident: e_1_2_3_94_2 doi: 10.1021/acs.joc.7b03259 – ident: e_1_2_3_21_2 doi: 10.1021/acs.chemrev.6b00005 – ident: e_1_2_3_85_2 doi: 10.1002/anie.202204719 – ident: e_1_2_3_28_2 doi: 10.1039/D0QO00460J – ident: e_1_2_3_49_2 doi: 10.1021/jacs.2c11501 – ident: e_1_2_3_75_2 doi: 10.1016/S0040-4020(01)87348-8 – ident: e_1_2_3_31_2 doi: 10.1055/s-0037-1610314 – ident: e_1_2_3_98_1 – ident: e_1_2_3_48_2 doi: 10.1021/jacs.2c09733 – ident: e_1_2_3_113_2 doi: 10.1021/jacs.0c00245 – ident: e_1_2_3_3_2 doi: 10.1039/c2md20347b – ident: e_1_2_3_107_2 doi: 10.1039/C6CS00107F – ident: e_1_2_3_24_2 doi: 10.1002/anie.201006017 – ident: e_1_2_3_91_2 doi: 10.1021/ja4042127 – ident: e_1_2_3_112_2 doi: 10.1002/anie.201908951 – ident: e_1_2_3_115_2 doi: 10.1021/jacs.2c09045 – ident: e_1_2_3_114_2 doi: 10.1002/anie.202011739 – ident: e_1_2_3_76_2 doi: 10.1002/anie.200600723 – ident: e_1_2_3_100_2 doi: 10.1021/acscatal.6b03399 – ident: e_1_2_3_68_2 doi: 10.1021/ja802906k – ident: e_1_2_3_27_2 doi: 10.1002/anie.202106352 – ident: e_1_2_3_101_2 doi: 10.1039/D3SC03258B – ident: e_1_2_3_116_2 doi: 10.1039/D3SC01373A – ident: e_1_2_3_25_1 – ident: e_1_2_3_86_2 doi: 10.1021/jacs.2c09248 – ident: e_1_2_3_67_2 doi: 10.1021/ar500437h – ident: e_1_2_3_105_2 doi: 10.1021/acs.accounts.9b00623 – ident: e_1_2_3_16_2 doi: 10.1021/acscentsci.0c01651 – ident: e_1_2_3_38_2 doi: 10.1038/s41557-021-00786-z – ident: e_1_2_3_4_2 doi: 10.1039/D1SC00161B – ident: e_1_2_3_111_2 doi: 10.1038/s41557-018-0181-x – ident: e_1_2_3_97_2 doi: 10.1039/D1SC01127H – ident: e_1_2_3_65_2 doi: 10.1515/pac-2019-1007 – volume: 351 start-page: 241 year: 2016 ident: WOS:000368098600032 article-title: Strain-release amination publication-title: SCIENCE doi: 10.1126/science.aad6252 – volume: 83 start-page: 2341 year: 2018 ident: WOS:000427094200067 article-title: Catalytic Asymmetric Dearomative [3+2] Cycloaddition of Electron-Deficient Indoles with All-Carbon 1,3-Dipoles publication-title: JOURNAL OF ORGANIC CHEMISTRY doi: 10.1021/acs.joc.7b03259 – volume: 143 start-page: 7648 year: 2021 ident: WOS:000657212800010 article-title: Use of Strain-Release for the Diastereoselective Construction of Quaternary Carbon Centers publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.1c03492 – volume: 76 start-page: 461 year: 1976 ident: WOS:A1976BY80200003 article-title: TRANSITION-METAL CATALYZED REARRANGEMENTS OF SMALL RING ORGANIC-MOLECULES publication-title: CHEMICAL REVIEWS – volume: 59 start-page: 20515 year: 2020 ident: WOS:000560930500001 article-title: Saturated Bioisosteres ofortho-Substituted Benzenes publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202004183 – volume: 47 start-page: 2558 year: 2014 ident: WOS:000340702000032 article-title: Transition-Metal-Catalyzed Asymmetric Allylic Dearomatization Reactions publication-title: ACCOUNTS OF CHEMICAL RESEARCH doi: 10.1021/ar500167f – volume: 62 year: 2023 ident: WOS:001008962500001 article-title: Lewis Acid Catalyzed Formal (3+2)-Cycloaddition of Bicyclo[1.1.0]butanes with Ketenes publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202304771 – volume: 18 start-page: 4300 year: 2016 ident: WOS:000382711200039 article-title: Hydrophosphination of Bicyclo[1.1.0]butane-1-carbonitriles publication-title: ORGANIC LETTERS doi: 10.1021/acs.orglett.6b02051 – volume: 66 start-page: 4704 year: 2001 ident: WOS:000169536700034 article-title: Cyclopentannulation of 3-alkylindoles: A synthesis of a tetracyclic subunit of the kopsane alkaloids publication-title: JOURNAL OF ORGANIC CHEMISTRY doi: 10.1021/jo015643r – volume: 12 start-page: 8706 year: 2021 ident: WOS:000654359200001 article-title: Catalytic (3+2) annulation of donor-acceptor aminocyclopropane monoesters and indoles publication-title: CHEMICAL SCIENCE doi: 10.1039/d1sc01127h – volume: 1 start-page: 830 year: 2016 ident: WOS:000389801600008 article-title: Catalytic Asymmetric Dearomatization by Transition-Metal Catalysis: A Method for Transformations of Aromatic Compounds publication-title: CHEM doi: 10.1016/j.chempr.2016.11.005 – volume: 13 start-page: ARTN 6056 year: 2022 ident: WOS:000868657300014 article-title: [2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes publication-title: NATURE COMMUNICATIONS doi: 10.1038/s41467-022-33827-3 – volume: 139 start-page: 17791 year: 2017 ident: WOS:000418204600023 article-title: Radical Multicomponent Carboamination of [1.1.1]Propellane publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.7b11865 – volume: 144 start-page: 7988 year: 2022 ident: WOS:000799180800007 article-title: Strain-Release [2π+2σ] Cycloadditions for the Synthesis of Bicyclo[2.1.1]hexanes Initiated by Energy Transfer publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c02976 – volume: 59 start-page: 7161 year: 2020 ident: WOS:000520307500001 article-title: Water-Soluble Non-Classical Benzene Mimetics publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202000548 – volume: 34 start-page: 62 year: 2017 ident: WOS:000392479800003 article-title: Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis publication-title: NATURAL PRODUCT REPORTS doi: 10.1039/c5np00076a – volume: 611 start-page: 721 year: 2022 ident: WOS:000869346300001 article-title: Synthesis of meta-substituted arene bioisosteres from [3.1.1]propellane publication-title: NATURE doi: 10.1038/s41586-022-05290-z – volume: 13 start-page: ARTN 7292 year: 2022 ident: WOS:000888871600011 article-title: How mono- and diphosphine ligands alter regioselectivity of the Rh-catalyzed annulative cleavage of bicyclo[1.1.0]butanes publication-title: NATURE COMMUNICATIONS doi: 10.1038/s41467-022-34837-x – volume: 15 start-page: 535 year: 2023 ident: WOS:000933339300001 article-title: A catalytic alkene insertion approach to bicyclo[2.1.1]hexane bioisosteres publication-title: NATURE CHEMISTRY doi: 10.1038/s41557-023-01135-y – volume: 45 start-page: 4172 year: 2006 ident: WOS:000238718500022 article-title: Pericyclic cascade reactions of (bicyclo[1.1.0]butylmethyl)amines publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.200600723 – volume: 17 start-page: 2839 year: 2019 ident: WOS:000461223700026 article-title: Saturated bioisosteres of benzene: where to go next? publication-title: ORGANIC & BIOMOLECULAR CHEMISTRY doi: 10.1039/c8ob02812e – volume: 83 start-page: 3998 year: 1961 ident: WOS:A19613058B00044 article-title: BICYCLO[2.1.1]HEXANE DERIVATIVES publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 145 start-page: 4304 year: 2023 ident: 001088127300001.45 publication-title: J. Am. Chem. Soc – volume: 94 start-page: 7780 year: 1972 ident: WOS:A1972N906500026 article-title: AG+-CATALYZED REARRANGEMENTS .14. INFLUENCE OF STRUCTURAL FEATURES ON COURSE OF BICYCLO[1.1.0)BUTANE REARRANGEMENTS CATALYZED BY SILVER(I) ION publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 14 start-page: 6585 year: 2023 ident: WOS:001012087800001 article-title: Lewis acid-catalyzed diastereoselective carbofunctionalization of bicyclobutanes employing naphthols publication-title: CHEMICAL SCIENCE doi: 10.1039/d3sc01373a – volume: 62 year: 2023 ident: WOS:001007996600001 article-title: General Synthesis of 3-Azabicyclo[3.1.1]heptanes and Evaluation of Their Properties as Saturated Isosteres publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202304246 – volume: 31 start-page: 3065 year: 2020 ident: WOS:000600917100012 article-title: Recent advances in the applications of [1.1.1]propellane in organic synthesis publication-title: CHINESE CHEMICAL LETTERS doi: 10.1016/j.cclet.2020.04.023 – volume: 62 start-page: ARTN e202309030 year: 2023 ident: WOS:001041551200001 article-title: Coordination Defect-Induced Frustrated Lewis Pairs in Polyoxo-metalate-Based Metal-Organic Frameworks for Efficient Catalytic Hydrogenation publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202309030 – volume: 48 start-page: 1149 year: 2015 ident: WOS:000353429400026 article-title: Ring-Strain-Enabled Reaction Discovery: New Heterocycles from Bicyclo[1.1.0]butanes publication-title: ACCOUNTS OF CHEMICAL RESEARCH doi: 10.1021/ar500437h – volume: 7 start-page: 432 year: 2021 ident: WOS:000634764100009 article-title: Advances in Catalytic Asymmetric Dearomatization publication-title: ACS CENTRAL SCIENCE doi: 10.1021/acscentsci.0c01651 – volume: 7 start-page: 1533 year: 2017 ident: WOS:000395726500003 article-title: Rhodium-Catalyzed Stereoselective Intramolecular Tandem Reaction of Vinyloxiranes with Alkynes: Atom- and Step-Economical Synthesis of Multifunctional Mono-, Bi-, and Tricyclic Compounds publication-title: ACS CATALYSIS doi: 10.1021/acscatal.6b03399 – volume: 40 start-page: 5671 year: 1999 ident: WOS:000081543000007 article-title: The annulation of 3-alkylindoles with 1,1-cyclopropanediesters publication-title: TETRAHEDRON LETTERS – volume: 14 start-page: 9696 year: 2023 ident: WOS:001064597400001 article-title: C(sp2)-H cyclobutylation of hydroxyarenes enabled by silver-p-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes publication-title: CHEMICAL SCIENCE doi: 10.1039/d3sc03258b – volume: 144 start-page: 21848 year: 2022 ident: WOS:000883756300001 article-title: Practical and Facile Access to Bicyclo[3.1.1]heptanes: Potent Bioisosteres of meta-Substituted Benzenes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c09733 – volume: 88 start-page: 496 year: 1966 ident: WOS:A19667263600021 article-title: BICYCLO[1.1.0]BUTANE CHEMISTRY .2. CYCLOADDITION REACTIONS OF 3-METHYLBICYCLO[1.1.0]BUTANECARBONITRILES . FORMATION OF BICYCLO[2.1.1]HEXANES publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY – volume: 64 start-page: 14046 year: 2021 ident: WOS:000709633100007 article-title: Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/acs.jmedchem.1c01215 – volume: 53 start-page: 662 year: 2020 ident: WOS:000526398000012 article-title: Silver-Catalyzed Activation of Terminal Alkynes for Synthesizing Nitrogen-Containing Molecules publication-title: ACCOUNTS OF CHEMICAL RESEARCH doi: 10.1021/acs.accounts.9b00623 – volume: 9 start-page: 2149 year: 2022 ident: WOS:000766792000001 article-title: Diastereoselective synthesis of 1,1,3,3-tetrasubstituted cyclobutanes enabled by cycloaddition of bicyclo[1.1.0]butanes publication-title: ORGANIC CHEMISTRY FRONTIERS doi: 10.1039/d2qo00167e – volume: 8 start-page: 18576 year: 2018 ident: WOS:000433428300048 article-title: Recent metal-catalysed approaches for the synthesis of cyclopenta[b]indoles publication-title: RSC ADVANCES doi: 10.1039/c8ra03480j – volume: 92 start-page: 751 year: 2020 ident: WOS:000537416000006 article-title: Recent advances in the chemistry of bicyclo- and 1-azabicyclo[1.1.0]butanes publication-title: PURE AND APPLIED CHEMISTRY doi: 10.1515/pac-2019-1007 – volume: 142 start-page: 5355 year: 2020 ident: WOS:000526392600047 article-title: Polarity-Reversal Strategy for the Functionalization of Electrophilic Strained Molecules via Light-Driven Cobalt Catalysis publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.0c00245 – volume: 30 start-page: 1 year: 2019 ident: WOS:000453250700001 article-title: Recent Advances in the Synthetic Chemistry of Bicyclo[1.1.1]pentane publication-title: SYNLETT doi: 10.1055/s-0037-1610314 – volume: 42 start-page: 1291 year: 1986 ident: WOS:A1986A540600007 article-title: CYCLOADDITIONS OF METHYLENECYCLOPROPANES AND STRAINED BICYCLO[N.1.0]ALKANES TO RADICOPHILIC OLEFINS publication-title: TETRAHEDRON – volume: 4 start-page: 515 year: 2013 ident: WOS:000315355800005 article-title: Escape from Flatland 2: complexity and promiscuity publication-title: MEDCHEMCOMM doi: 10.1039/c2md20347b – volume: 24 start-page: 1268 year: 2022 ident: WOS:000743540500001 article-title: Investigating Bicyclobutane-Triazolinedione Cycloadditions as a Tool for Peptide Modification publication-title: ORGANIC LETTERS doi: 10.1021/acs.orglett.1c04071 – volume: 135 start-page: 9283 year: 2013 ident: WOS:000321236600013 article-title: Enantioselective Synthesis of Cyclobutanes via Sequential Rh-catalyzed Bicyclobutanation/Cu-catalyzed Homoconjugate Addition publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/ja403811t – volume: 59 start-page: 2618 year: 2020 ident: WOS:000494501000001 article-title: Photochemical Strain-Release-Driven Cyclobutylation of C(sp3)-Centered Radicals publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201908951 – volume: 60 start-page: 212 year: 2021 ident: WOS:000585833800001 article-title: α-Selective Ring-Opening Reactions of Bicyclo[1.1.0]butyl Boronic Ester with Nucleophiles publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202011739 – year: 2023 ident: WOS:000935916900001 article-title: A General and Modular Approach to BCP Alkylamines via Multicomponent Difunctionalization of [1.1.1]Propellane publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c13298 – volume: 15 start-page: 685 year: 2023 ident: WOS:000959282800003 article-title: Catalytic undirected borylation of tertiary C-H bonds in bicyclo[1.1.1]pentanes and bicyclo[2.1.1]hexanes publication-title: NATURE CHEMISTRY doi: 10.1038/s41557-023-01159-4 – volume: 143 start-page: 9729 year: 2021 ident: WOS:000672592000004 article-title: Twofold Radical-Based Synthesis of N,C-Difunctionalized Bicyclo[1.1.1]pentanes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.1c04180 – volume: 59 start-page: 3917 year: 2020 ident: WOS:000509718000001 article-title: 1,3-Difunctionalizations of [1.1.1]Propellane via 1,2-Metallate Rearrangements of Boronate Complexes publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201914875 – volume: 12 start-page: 4646 year: 2021 ident: WOS:000637925000001 article-title: Emergent synthetic methods for the modular advancement of sp3-rich fragments publication-title: CHEMICAL SCIENCE doi: 10.1039/d1sc00161b – volume: 11 start-page: 117 year: 2019 ident: WOS:000456665900007 article-title: Carbopalladation of C-C σ-bonds enabled by strained boronate complexes publication-title: NATURE CHEMISTRY doi: 10.1038/s41557-018-0181-x – volume: 145 start-page: 10960 year: 2023 ident: WOS:000983351000001 article-title: Skeletal Editing Approach to Bridge-Functionalized Bicyclo[1.1.1]pentanes from Azabicyclo[2.1.1]hexanes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.3c02616 – volume: 22 start-page: 1266 year: 2016 ident: WOS:000368922500012 article-title: Formal Synthesis of Solanoeclepin A: Enantioselective Allene Diboration and Intramolecular [2+2] Photocycloaddition for the Construction of the Tricyclic Core publication-title: CHEMISTRY-A EUROPEAN JOURNAL doi: 10.1002/chem.201504894 – volume: 144 start-page: 23685 year: 2022 ident: WOS:000903236700001 article-title: Photochemical Intermolecular [3Σ+2Σ]-Cycloaddition for the Construction of Aminobicyclo[3.1.1]heptanes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c11501 – volume: 56 start-page: 5718 year: 2020 ident: WOS:000537959100028 article-title: Strain release - an old tool for new transformations publication-title: CHEMICAL COMMUNICATIONS doi: 10.1039/d0cc01771j – volume: 60 start-page: 24754 year: 2021 ident: WOS:000682494400001 article-title: Bridge Functionalisation of Bicyclo[1.1.1]pentane Derivatives publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202106352 – volume: 6 start-page: 1589 year: 2020 ident: WOS:000558678900014 article-title: Shaping Molecular Landscapes: Recent Advances, Opportunities, and Challenges in Dearomatization publication-title: CHEM doi: 10.1016/j.chempr.2020.06.015 – volume: 144 start-page: 20875 year: 2022 ident: WOS:000879942700001 article-title: Palladium Hydride-Enabled Hydroalkenylation of Strained Molecules publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c09045 – volume: 116 start-page: 9816 year: 2016 ident: WOS:000383410100006 article-title: Arene-Alkene Cycloaddition publication-title: CHEMICAL REVIEWS doi: 10.1021/acs.chemrev.6b00005 – volume: 14 start-page: 9885 year: 2023 ident: WOS:001058076900001 article-title: Synthesis of polysubstituted bicyclo[2.1.1]hexanes enabling access to new chemical space publication-title: CHEMICAL SCIENCE doi: 10.1039/d3sc03083k – volume: 144 start-page: 20207 year: 2022 ident: WOS:000887076900001 article-title: Synthesis of Polysubstituted 2-Oxabicyclo[2.1.1]hexanes via Visible- Light-Induced Energy Transfer publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c09248 – volume: 3 start-page: 1539 year: 2023 ident: WOS:001012251300001 article-title: Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes publication-title: JACS AU doi: 10.1021/jacsau.3c00014 – volume: 15 start-page: 1155 year: 2023 ident: WOS:001000894300001 article-title: 2-Oxabicyclo[2.1.1]hexanes as saturated bioisosteres of the ortho-substituted phenyl ring publication-title: NATURE CHEMISTRY doi: 10.1038/s41557-023-01222-0 – volume: 47 start-page: 7996 year: 2018 ident: WOS:000448662800009 article-title: Recent advances in chemical dearomatization of nonactivated arenes publication-title: CHEMICAL SOCIETY REVIEWS doi: 10.1039/c8cs00389k – volume: 143 start-page: 21223 year: 2021 ident: WOS:000731578000001 article-title: Photochemical Formal (4+2)-Cycloaddition of Imine-Substituted Bicyclo[1.1.1]pentanes and Alkenes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.1c10541 – volume: 9 start-page: 8 year: 2020 ident: WOS:000501671600001 article-title: Selected Topics in the Syntheses of Bicyclo[1.1.1]Pentane (BCP) Analogues publication-title: ASIAN JOURNAL OF ORGANIC CHEMISTRY doi: 10.1002/ajoc.201900589 – volume: 144 start-page: 12961 year: 2022 ident: WOS:000828488000001 article-title: Dicarbofunctionalization of [1.1.1]Propellane Enabled by Nickel/Photoredox Dual Catalysis: One-Step Multicomponent Strategy for the Synthesis of BCP-Aryl Derivatives publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.2c05304 – volume: 58 start-page: 9851 year: 2019 ident: WOS:000476615900024 article-title: Total Syntheses of (+)-Aquatolide and Related Humulanolides publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201904404 – volume: 605 start-page: 477 year: 2022 ident: WOS:000793701100001 article-title: Intermolecular [2π+2σ]-photocycloaddition enabled by triplet energy transfer publication-title: NATURE doi: 10.1038/s41586-022-04636-x – volume: 7 start-page: 3967 year: 2020 ident: WOS:000592311700013 article-title: Progresses in organocatalytic asymmetric dearomatization reactions of indole derivatives publication-title: ORGANIC CHEMISTRY FRONTIERS doi: 10.1039/d0qo01124j – volume: 7 start-page: 2531 year: 2020 ident: WOS:000562454200020 article-title: Photoinduced strategies towards strained molecules publication-title: ORGANIC CHEMISTRY FRONTIERS doi: 10.1039/d0qo00460j – volume: 21 start-page: 7199 year: 2019 ident: WOS:000487577200003 article-title: A Selective Synthesis of 2,2-Difluorobicyclo[1.1.1]pentane Analogues: "BCP-F2" publication-title: ORGANIC LETTERS doi: 10.1021/acs.orglett.9b02026 – volume: 61 year: 2022 ident: WOS:000890467600001 article-title: Diboron(4)-Catalyzed Remote [3+2] Cycloaddition of Cyclopropanes via Dearomative/Rearomative Radical Transmission through Pyridine publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202214507 – volume: 580 start-page: 220 year: 2020 ident: WOS:000522805100001 article-title: Copper-mediated synthesis of drug-like bicyclopentanes publication-title: NATURE doi: 10.1038/s41586-020-2060-z – volume: 12 start-page: 4807 year: 2014 ident: WOS:000338118400002 article-title: Recent advances in dearomatization of heteroaromatic compounds publication-title: ORGANIC & BIOMOLECULAR CHEMISTRY doi: 10.1039/c4ob00371c – volume: 118 start-page: ARTN e2108881118 year: 2021 ident: WOS:000685035200004 article-title: 1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/ meta-substituted arenes publication-title: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA doi: 10.1073/pnas.2108881118 – volume: 45 start-page: 4590 year: 2016 ident: WOS:000381438600010 article-title: Ag-catalyzed C-H/C-C bond functionalization publication-title: CHEMICAL SOCIETY REVIEWS doi: 10.1039/c6cs00107f – volume: 6 start-page: ARTN 9 year: 2023 ident: WOS:000913525100001 article-title: Bicyclobutanes as unusual building blocks for complexity generation in organic synthesis publication-title: COMMUNICATIONS CHEMISTRY doi: 10.1038/s42004-022-00811-3 – volume: 13 start-page: 950 year: 2021 ident: WOS:000701641300003 article-title: An intramolecular coupling approach to alkyl bioisosteres for the synthesis of multisubstituted bicycloalkyl boronates publication-title: NATURE CHEMISTRY doi: 10.1038/s41557-021-00786-z – volume: 618 start-page: 513 year: 2023 ident: WOS:001003548000001 article-title: General access to cubanes as benzene bioisosteres publication-title: NATURE doi: 10.1038/s41586-023-06021-8 – volume: 82 start-page: 13517 year: 2017 ident: WOS:000418392600055 article-title: Pd-Catalyzed Dearomative [3+2] Cycloaddition of 3-Nitroindoles with 2-Vinylcyclopropane-1,1-dicarboxylates publication-title: JOURNAL OF ORGANIC CHEMISTRY doi: 10.1021/acs.joc.7b02624 – volume: 56 start-page: 1351 year: 2017 ident: WOS:000394997700031 article-title: Rhodium( I)-Catalyzed Intermolecular Aza-[4+3] Cycloaddition of Vinyl Aziridines and Dienes: Atom-Economical Synthesis of Enantiomerically Enriched Functionalized Azepines publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201609608 – volume: 129 start-page: 9631 year: 2007 ident: WOS:000248484400044 article-title: C-2/C-3 annulation and C-2 alkylation of indoles with 2-alkoxycyclopropanoate esters publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/ja067821+ – volume: 61 start-page: ARTN e202204719 year: 2022 ident: WOS:000790027100001 article-title: Beyond Bioisosteres: Divergent Synthesis of Azabicyclohexanes and Cyclobutenyl Amines from Bicyclobutanes publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202204719 – volume: 17 start-page: 3892 year: 2015 ident: WOS:000359393800064 article-title: Total Synthesis of Aquatolide publication-title: ORGANIC LETTERS doi: 10.1021/acs.orglett.5b01888 – volume: 130 start-page: 6924 year: 2008 ident: WOS:000256301200016 article-title: Rhodium(I)-catalyzed cycloisomerizations of bicyclobutanes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/ja802906k – volume: 135 start-page: 7851 year: 2013 ident: WOS:000319856700016 article-title: Copper-Catalyzed Highly Enantioselective Cyclopentannulation of Indoles with Donor-Acceptor Cyclopropanes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/ja4042127 – volume: 62 start-page: 1078 year: 2019 ident: WOS:000459223600002 article-title: Cubanes in Medicinal Chemistry publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/acs.jmedchem.8b00888 – volume: 51 start-page: 2145 year: 2022 ident: WOS:000760929500001 article-title: Visible-light induced dearomatization reactions publication-title: CHEMICAL SOCIETY REVIEWS doi: 10.1039/c9cs00311h – volume: 12 start-page: 5034 year: 2020 ident: WOS:000567416500001 article-title: Recent Advances in Silver-Catalyzed Transformations of Electronically Unbiased Alkenes and Alkynes publication-title: CHEMCATCHEM doi: 10.1002/cctc.202000743 – volume: 7 start-page: 595 year: 2015 ident: WOS:000349917900008 article-title: Gold- and Silver-Catalyzed Intramolecular Cyclizations of Indolylcyclopropenes for the Divergent Synthesis of Azepinoindoles and Spiroindoline Piperidines publication-title: CHEMCATCHEM doi: 10.1002/cctc.201402940 – volume: 13 start-page: 11721 year: 2022 ident: WOS:000848123300001 article-title: Bicyclobutanes: from curiosities to versatile reagents and covalent warheads publication-title: CHEMICAL SCIENCE doi: 10.1039/d2sc03948f – volume: 145 start-page: 12324 year: 2023 ident: WOS:001005914100001 article-title: ortho-Selective Dearomative [2π+2σ] Photocycloadditions of Bicyclic Aza-Arenes publication-title: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY doi: 10.1021/jacs.3c02961 – volume: 381 start-page: 75 year: 2023 ident: WOS:001030999200030 article-title: Dearomative ring expansion of thiophenes by bicyclobutane insertion publication-title: SCIENCE doi: 10.1126/science.adh9737 – year: 2022 ident: WOS:000890722600001 article-title: Bicyclo[2.1.1]hexanes by Visible Light-Driven Intramolecular Crossed [2+2] Photocycloadditions publication-title: ORGANIC LETTERS doi: 10.1021/acs.orglett.2c03606 – volume: 13 start-page: 5096 year: 2023 ident: WOS:000971587200001 article-title: Pyridine-Boryl Radical-Catalyzed [2?+2?] Cycloaddition of with Alkenes publication-title: ACS CATALYSIS doi: 10.1021/acscatal.3c00305 – year: 2023 ident: 001088127300001.44 publication-title: ChemRxiv – volume: 61 start-page: ARTN e202205103 year: 2022 ident: WOS:000810708000001 article-title: A Practical and Scalable Approach to Fluoro-Substituted Bicyclo[1.1.1]pentanes publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.202205103 – volume: 50 start-page: 4068 year: 2011 ident: WOS:000290662500006 article-title: Dearomatization Strategies in the Synthesis of Complex Natural Products publication-title: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION doi: 10.1002/anie.201006017 – volume: 52 start-page: 6752 year: 2009 ident: WOS:000271427900027 article-title: Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/jm901241e |
| SSID | ssj0028806 |
| Score | 2.6557512 |
| Snippet | Bicyclo[2.1.1]hexanes (BCHs) are becoming ever more important in drug design and development as bridged scaffolds that provide underexplored chemical space,... |
| Source | Web of Science |
| SourceID | webofscience crossref wiley |
| SourceType | Enrichment Source Index Database Publisher |
| SubjectTerms | Bicyclic Compounds Bioisosteres Chemistry Chemistry, Multidisciplinary Cycloaddition Heterocycles Physical Sciences Science & Technology Strained Molecules |
| Title | Silver‐Catalyzed Dearomative [2π+2σ] Cycloadditions of Indoles with Bicyclobutanes: Access to Indoline Fused Bicyclo[2.1.1]hexanes |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Fanie.202310066 http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestApp=WOS&DestLinkType=FullRecord&UT=001088127300001 |
| Volume | 62 |
| WOS | 001088127300001 |
| WOSCitedRecordID | wos001088127300001 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NTtwwELYQF7i0hVJ1aUE-IPVQJax_kqx72wZWUAkOLUhICEW24wgEbKpu9rB7QkLquW_GO_RJmHGyKVsJUdGbLY0jx5nxfHZmviFkK2eum2iZBMoUMpBS5EFP5NDV1hYisbrwf88PDuO9Y_nlJDp5kMVf80O0F25oGX6_RgPXZrT9hzQUM7BDLP7N0G3CJowBW4iKvrb8URyUs04vEiLAKvQz1sYu354fPueV5jzQPGj1XmfwkujZfOtgk8twXJnQTv-icvyfF3pFXjSQlPZrHVohC264SpbSWSW41-TntwuMn_598yvFy57J1OV0ByykvPas4fSU39185He3ZzSd2KsSQ5S8NtOyoPtDTxlF8b6Xfr6wKGDGgEjd6BPt-2qNtCprMXgDOhiP4OmN4CkPWcjOzjEHx43WyPFg9yjdC5r6DYGFY1wcmCTixsai6EUqVioySrkITmwuYlrohEW5QX64bqxVkktlrAWsksCOYoTMu9yIN2RxWA7dW0K1YgVAuUIKpCi0rgc-VhoWOxNb2KHyDglm3y-zDbk51ti4ympaZp7h6mbt6nbIh1b-e03r8ajk1kN1aKXxMN0DdIR8_9DuEPYvYmkzNyQcqDqEe314YgZZ_3B_t-2tP2fQO7KMbcyh5Ml7slj9GLsNAFOV2fQGcw-LMRaw |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1LT9wwEB5ReqAX6FMs5eEDUg9VwvqRZM1tSVnttrCHFqRKCEWx46iosEHd7AFOSEg995_xH_pL6nEedCtVrdpbEo0j25nxPDLzDcB2Rk03SkXkSZULTwieeT2e2dtU65xHOs3d3_PDcTg8Fm8_Bk02IdbCVPgQbcANJcOd1yjgGJDeuUcNxRJsH7t_U9SbD-AhtvV2XtX7FkGKWfasCow497APfYPb2GU78-Pn9NKcDpo3W53eGayAamZcpZt89mel8vX1L2CO_7Wkx7BcW6WkX7HRE1gwk6ewFDfN4J7B1w9nmEL9_eZbjPGeq2uTkTdWSIoLBxxOTtjdzWt2d3tK4it9XmCWkmNoUuRkNHGoUQRDvmTvTCOBmlmj1Ex3Sd81bCRlUZHZJZDBbGrfXhOeMJ_69PQTluGY6XM4HuwfxUOvbuHgaevJhZ6KAqZ0yPNeIEMpAyWlCazTZgKa8jSiQaYQIq4bpjLKhFRaW3MlsoeK4iLrMsVfwOKkmJhVIKmkubXmcsERpVCbnlWzQtHQqFDbQyrrgNd8wETX-ObYZuM8qZCZWYK7m7S724FXLf1lhezxW8rtn_mhpUZ_umcNJIT8t9cdoH9DFtdzQ8yBsgPMMcQfZpD0x6P99m7tXwZtwdLw6PAgORiN372ER_gcSypZtA6L5ZeZ2bC2Vak2nfT8AO7kGss |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1ba9RAFD5oBfXFe3G9zkPBB0maueQyvq3ZLl0vi6iFQikhcwkW66a42Yf2qSD47D_rf_CXOGeSjV1BFH3LhG_CzOScOWcu5zsAG4baKC1FGkhViUAIboKMG1csta54qsvKn56_nibbO-LFbrx7Loq_5YfoN9xQM_x8jQp-ZKrNn6ShGIEdYvJvimbzIlwSSZShXI_e9gRSzElnG1_EeYBp6Je0jRHbXK2_YpZWTNCq1-rNzvg6lMsGt7dNPoaLRoX65Bcux__p0Q241vmkZNgK0U24YGe34Eq-TAV3G76-O8AL1N9Pv-W423N8Yg0ZORWpP3nacLLHzk6fsrMv-yQ_1oc13lHy4kzqikxmnjOK4IYveX6gEaAWziW182dk6NM1kqZuYa4HZLyYu693wD0W0pDuf8AgHDu_Azvjrff5dtAlcAi0W8clgUpjpnTCqyyWiZSxktLGbslmY1ryMqWxUUgQFyWlTI2QSmvnrKRuSlFcmIgpvg5rs3pm7wIpJa2cL1cJjhyF2mbOyApFE6sS7aYoM4Bg-f8K3bGbY5KNw6LlZWYFjm7Rj-4AnvT4o5bX47fIjfPi0KNxNZ059wgJ_93zAOjfwPKubcg40AyAeXn4QwuK4XSy1Zfu_Uulx3D5zWhcvJpMX96Hq_ga4ylZ-gDWms8L-9A5Vo165HXnB5-4GYM |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Silver-Catalyzed+Dearomative+%5B2%CF%80%2B2%CF%83%5D+Cycloadditions+of+Indoles+with+Bicyclobutanes%3A+Access+to+Indoline+Fused+Bicyclo%5B2.1.1%5Dhexanes&rft.jtitle=Angewandte+Chemie+International+Edition&rft.au=Tang%2C+Lei&rft.au=Xiao%2C+Yuanjiu&rft.au=Wu%2C+Feng&rft.au=Zhou%2C+Jin-Lan&rft.date=2023-11-27&rft.pub=Wiley&rft.eissn=1521-3773&rft.volume=62&rft.issue=48&rft_id=info:doi/10.1002%2Fanie.202310066&rft_id=info%3Apmid%2F37822277&rft.externalDBID=n%2Fa&rft.externalDocID=001088127300001 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1433-7851&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1433-7851&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1433-7851&client=summon |